The onset and manifestations of irritable bowel syndrome(IBS)is associated with several factors,and the pathophysiology involves various central and peripheral mechanisms.Most studies indicate that the management of gut microbiota could significantly affect the improvement of subjective disorders in patients ...
Although results between studies are difficult to compare because of differences in study design, probiotic dose, strain, and duration of therapy, some studies show symptom improvement. Lactobacilli are found among the normal bacterial flora of the gastrointestinal tract, and Lactobacillus plantarum (Lp...
The primary outcome is global symptoms improvement. The secondary outcomes will include individual IBS symptom scores, emotional response, and adverse events. The conventional pair-wise meta-analysis will be performed using Stata V.14.0 and be pooled using a random-effects model. We will use ...
While our analyses suggest that probiotic use may be associated with improvement in IBS symptoms compared to placebo, these results should be interpreted with caution, given the methodological limitations of contributing studies. Probiotics warrant further study as a potential therapy for IBS. 展开 关键...
They can also reduce visceral hypersensitivity associated with both inflammation and psychological stress. Probiotics can alter colonic fermentation and stabilize the colonic microbiota. Several large randomized, placebo-controlled trials of adequate design have shown an improvement in flatulence and abdominal ...
Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that affects between 5 and 10% of the general population worldwide. The current symptom criteria restrict the diagnosis to recurrent abdominal pain associated with al
Probiotic therapy was associated with more improvement than placebo administration in overall symptom response (RR: 1.82, 95% CI 1.27 to 2.60) and quality of life (QoL) (SMD: 0.29, 95% CI 0.08 to 0.50), but not in individual IBS symptoms. Single probiotics, a low dose, and a short ...
Although participants taking BB-12 did show an improvement in defecation frequency over the placebo, the two different doses of BB-12 that were tested produced similar results. Researchers suggested this might be because BB-12 reached a ceiling effect with the 1 billion CFU dose. ...
48 A trend toward improvement was noted, however, for a reduction in the number of unformed bowel motions in treated patients with diarrhea. Oligofructose and inulin are probiotic agents reported to increase bifidobacteria in feces and increase stool weight, which makes them attractive in the ...
Probiotics and prebiotics Gut-brain interactions are the key to IBS. To keep the gut health in check and help with the IBS symptoms, many medical professionals recommend supplementation with probiotics and prebiotics. Multiple studies have shown that taking probiotics can help reduce stomach pain and...