(C) 2000 Lippincott Williams & Wilkins, Inc.doi:10.1097/00132583-200005050-00002CotelingamJames D.Pathology Case ReviewsCotelingam JD. Bone marrow interpretation: the science and the art. Pathol Case Rev 2000;5:239-251.
In general, a bone marrow examination should be considered if: • Circulating immature cells are identified on peripheral smear (blasts, etc); • Severe pancytopenia (decreased numbers of all cell types); • Very low reticulocyte counts (<0.1%); • Circulating nucleated RBCs; • ...
THE BONE MARROW BIOPSY PROCEDURE The bone marrow biopsy is a routine technique in the diagnosis of hematologic disorders, metastatic tumors, and infectious and metabolic diseases. Experience in interpretation of marrow biopsies is a valuable asset to the surgical pathologist. The major indications for ...
However, antemortem blood analyses are not always available, and interpretation of hematopoietic cytomorphologic examination results becomes difficult to impossible shortly after death. Postmortem bone marrow should be collected as soon as possible after death or euthanasia, preferably within 30 minutes. ...
Punctate reticulocytes in cats are evident when blood is stained with new methylene blue, but they are not counted as reticulocytes on the CBC and have the same appearance as mature erythrocytes on routine blood smear examination. Fig. 13-8 Hemopoietically active bone marrow, femur, calf.Note...
10.The Study of Zhe Correlation between Traditional Medical Syndrome and the Interpretation of Laboratory in Myelodysplastic Syndrome;骨髓增生异常综合征的实验室检查与中医辨证相关性的研究 11.The study on the union between marrow smear and marrow biopsy in the myelodysplastic syndrome diagnosis骨髓涂片联合...
Healthy bone marrow cell (BMC) infusion improves renal function and limits renal injury in a model of chronic kidney disease (CKD) in rats. However, BMCs derived from rats with CKD fail to retain beneficial effects, demonstrating limited therapeutic efficacy. Statins have been reported to improve...
Bone marrow fibrosis represents an important structural change in the marrow that interferes with some of its normal functions. The aetiopathogenesis of fibrosis is not well established except in its primary form. The present review consolidates current
BM smear revealed severe anemia, lymphopenia, and dysplastic morphologic findings of erythroblasts, neutrophils, and megakaryocytes. Trephine biopsy revealed hypercellular marrow dyserythropoiesis, plasmacytosis, lymphocytosis, histiocytosis, hemophagocytosis, and the absence of granulomas or carcinoma. ...
The smear is examined for normal cell morphology and myeloid vs. erythroid cell types. The myeloid to erythroid (M:E) ratio is calculated as an indication of bone marrow activity, and this ratio varies between 0.5:1 and 3:1 depending on the species. The maturation index, or ratio of...