Bone Marrow CellsAlthough bone marrow is known as a primary lymphoid organ, its potential to serve as a secondary immune organ has hardly been explored. Here we demonstrate that naive, antigen-specific T cells home to bone marrow, where they can be primed. to T cells in bone marrow is ...
For most individuals, the bone marrow comprises 3.5% to 6% of total body weight. It is the major organ of hematopoiesis and is both a primary and secondary lymphoid organ that provides an environment for cell development and immunologic interaction (15). The marrow consists of hematopoietic cells...
Bone marrow can function as a lymphoid organ during a primary immune response under conditions of disrupted lymphocyte trafficking. J Immunol 1997; 158: 3716–3720. CAS PubMed Google Scholar Dejbakhsh-Jones S, Jerabek L, Weissman IL, Strober S . Extrathymic maturation of alpha beta T cells...
A survey of the literature shows that Dominic1in 1902 observed focal collections of lymphocytes in the bone marrow. Longcope2 described these nodules in th... RJW Ams 被引量: 0发表: 2007年 Scheme of lingual tonsil ('lymphoepithelial tissue') The lymphoid follicles are capped by a corona (...
In terrestrial vertebrates, bone tissue constitutes the ‘osteoimmune’ system, which functions as a locomotor organ and a mineral reservoir as well as a primary lymphoid organ where haematopoietic stem cells are maintained. Bone and mineral metabol
bone marrow and are found in the circulation as well as in lymphoid and non-lymphoid tissue. In humans, circulating dendritic cells can be divided into two types of (classical)myeloid DCs(mDCs), recognized by the expression of eitherblood dendritic cellantigen-1 (BDCA-1) or BDCA-3, and...
Bone Marrow Lymphoid Infiltrates 作者:Anagnostou, Demitra; Matutes, Estella; Anagnostou, Dimitra 出版年:2012-10 页数:305 定价:$ 213.57 ISBN:9781447141730 豆瓣评分 目前无人评价 评价: 写笔记 写书评 加入购书单 分享到 + 加入购书单
The production of lymphoid nodules in the bone marrow of the domestic pigeon, following splenectomyFirst page of articledoi:10.1002/aja.1000710203H. E. JordanUniversity of Virginia, Charlottesville, and Syracuse University, New YorkJ. M. Robeson...
A requirement for MEF2C within bone marrow B-lymphoid cells was also documented using B-cell-specific Mb-1-Cre. This led to a reduction of B cells in both bone marrow and spleen of neonates. Although peripheral cellularity of B cells was corrected in adult mice, bone marrow B lymphopoiesis...
et al. Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism. J. Exp. Med. 203, 2683–2690 (2006). 20. Sellars, M., Reina-San-Martin, B., Kastner, P. & Chan, S. Ikaros controls isotype selection during immunoglobulin class switch ...