A bone-marrow niche
在骨髓利基(bone marrow niche)中,造骨蛋白osteopontin(OPN)扮演维持造血干细胞静止状态的角色,同时也可负向调控 … ntur.lib.ntu.edu.tw|基于2个网页 2. 骨髓壁龛 比如文绉绉的骨髓壁龛(bone marrow niche),其实就是骨髓微环境,即论文中骨髓间充质干细胞存在的地方。这样大家都容易 … ...
et al. Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization. Nat Cell Biol 22, 38–48 (2020). https://doi.org/10.1038/s41556-019-0439-6 Download citation Received15 July 2019 Accepted20 November 2019 Published23 December 2019...
Mobilization of hematopoietic stem cells from the bone marrow niche to the blood compartment. Stem Cell Res Ther 2011; 2: 13 [PMID: 21418553]Hoggatt J, Pelus LM. Mobilization of hematopoietic stem cells from the bone marrow niche to the blood compartment[ J]. Stem Cell Res Ther, 2011, 2...
Little is known about how leukemia cells alter the bone marrow (BM) niche to facilitate their own growth and evade chemotherapy. Here, we provide evidence that acute myeloid leukemia (AML) blasts remodel the BM niche into a leukemia growth-permissive and
Myeloid-biased hematopoietic stem cells (MB-HSCs) play critical roles in recovery from injury, but little is known about how they are regulated within the bone marrow niche. Here we describe an auto-/paracrine physiologic circuit that controls quiescence of MB-HSCs and hematopoietic progenitors mark...
Myelin-reactive T cells “home” to bone marrow and influence myelopoiesis The bone marrow niche harbors environmental factors that can attract T cells from circulation and lymphoid organs (Di Rosa and Pabst, 2005; Li et al., 2007; Melenhorst et al., 2009). As myelopoiesis is augmented in ...
Bone marrow stem cells: current and emerging concepts. Ann. N. Y. Acad. Sci. 1335, 32–44 (2015). Article CAS PubMed Google Scholar Mendez-Ferrer, S. et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 466, 829–834 (2010). Article CAS PubMed ...
Here we review recent progress in characterizing the composition of the HSC bone-marrow microenvironment, known as the HSC niche. During homeostasis, HSCs, and therefore putative bone-marrow HSC niches, are located near bone surfaces or are associated with the sinusoidal endothelium. The molecular ...
et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 466, 829–834 (2010). CAS PubMed PubMed Central Google Scholar Brazill, J. M., Beeve, A. T., Craft, C. S., Ivanusic, J. J. & Scheller, E. L. Nerves in bone: evolving concepts in pain...