Bone marrow is the most common site of extranodal involvement in lymphoid neoplasms, and evaluation of bone marrow is an important process in the work-up of patients with lymphoma. Different lymphomas often demonstrate characteristic infiltration patterns in the bone marrow. Familiarity with patterns ...
Multiple studies have found that FDG PET/CT in the initial diagnosis work-up detects more bone marrow involvement in lymphoma patients thus are more sensitive and more accurate than bilateral bone marrow biopsy performed at the iliac crest. At the same time, it has been shown that BMB ...
Bone MarrowTrephine BiopsyDiffuse Large Cell LymphomaNon-Hodgkin’s LymphomaLymphoproliferative DiseaseLymphoma StagingOBJECTIVE: To assess the frequency of bone marrow involvement in different stages of diffuse large B cell lymphoma patients. STUDY DESIGN : A cross sectional interventional study. PLACE AND...
Bone marrow involvement in anaplastic large cell lymphoma. Immunohistochemical detection of minimal disease and its prognostic significance. Bone marrow involvement by anaplastic large cell anaplastic large cell (ALC) lymphoma can be difficult to detect on routine morphologic examination alone. ... Fraga,...
The signal obtained is dependent on bone marrow cellularity and the proportions of haemopoietic tissue, fat, tumour and fibrous tissue present. MRI is a sensitive method of detecting bone marrow involvement in Hodgkin's disease and high grade non-Hodgkin's lymphoma and provides a complimentary tool...
Bone marrow involvement (BMI) was determined locally on BM trephine biopsy. Fresh blood samples were centrally collected for flow cytometry and DGGE PCR analyses aiming at detecting circulating neoplastic T cells by aberrant immunophenotype or a monoclonal TCR rearrangement. Total metabolic tumor volume ...
Five patterns of bone marrow infiltration by non-Hodgkin lymphoma or Hodgkin lymphoma are currently recognized, but a true follicular pattern of bone marrow involvement by follicular lymphoma has not been described. In 260 bone marrow trephine biopsy specimens involved by follicular lymphoma, we identif...
From 1975 to 1988, 50 patients with lymph node biopsy-documented diffuse large-cell lymphoma (DLCL) presented with bone marrow involvement. Twenty-four patients (48%) had large-cell lymphoma (LCL) in the bone marrow and were compared with 19 (38%) patients who had small cleaved-cell lymphom...
A 16-year-old boy with generalized myalgia and petechial hemorrhage was found to have a diffuse infiltrative disease in his bone marrow (BM). The BM aspirate contained a dense population of vacuolated blast-like cells. The BM biopsy displayed compact sheets of small round cells with clear cyt...