Inflammatory lesions of rat bone marrow are uncommon. Because the marrow parenchyma is filled with inflammatory cell types, recognizing certain inflammatory conditions is difficult. Of the types of inflammation that are diagnosed on histology, acute (neutrophil dominant), chronic (lymphocytes, plasma ce...
Importantly, inflammation exerts profoundly different effects on normal bone marrow niches in these malignancies, and we provide context for possible drivers of these divergent effects. We explore the role of tumour cells in inflammatory changes, as well as the role of cellular constituents of normal...
inflammationafter IRI. The regulation of sphingosine 1-phosphate receptors also significantly affected the development of AKI in animal models. Bajwa et al.124found that allogeneic S1pr3−/−bone marrow-derived DCs (BMDCs) preventrenal IRIthrough interaction in the spleen and induction of spleen ...
Obesity induces macrophages to infiltrate the CLSs of eWAT, and the presence of these ATMs is closely correlated with lipid turnover and chronic systemic inflammation25. It was unknown whether inhibition of these actions by depleting ATMs would be able to restore bone marrow homeostasis. After inj...
Wu et al. highlighted the therapeutic role of miR-34a-containing bone marrow mesenchymal stem cell (BMSC)-derived miR-34a in RA-FLSs. The authors’ investigation indicated that miR-34a ameliorates abnormal RA-FLS proliferation and inflammation by targeting cyclin I and further activating ATM/ATR/...
called primary autoimmune myelofibrosis has been recognized relatively recently [23]. In this disorder, in addition to myelofibrosis, collections of lymphoid cells in the marrow are an important morphological feature. This condition is not associated with any other features of a primary autoimmune ...
Inverse Regulation of Inflammation and Mitochondrial Function in Adipose Tissue Defines Extreme Insulin Sensitivity in Morbidly Obese Patients Obesity is associated with insulin resistance, a major risk factor for type 2 diabetes and cardiovascular disease. However, not all obese individuals are i... M...
摘要: Publication » Impact Of Stem Cells Originated From Bone Marrow Of Healthy, Pulmonary And Extrapulmonary Acute Lung Injury Models On Lung Inflammation And Remodeling.会议时间: 2012/05/01 收藏 引用 批量引用 报错 分享 全部来源 求助全文 ResearchGate atsjournals.org 相似文献Bone marow-...
is only the first step in successful migration. Tumor cells, like migrants, must survive a journey to a distant destination and must find a hospitable place to land, establish themselves, and flourish. To accomplish successful metastasis to the bone marrow, cancer cells hijack several properties ...
Subchondral bone marrow lesions A bone marrow lesion (BML), or so-called “bone marrow edema”2 or “bone marrow edema-like abnormality”,3 describes a noncystic, ill-defined, high-signal area on T2-weighted or proton density-weighted MRI.4 BMLs are divided into the subchondral type and ...