Bone marrow transplantation in childhood is an established treatment modality for aplastic anemia, the acute and chronic leukemias, and severe combined immune deficiency. Recently, experience with this treatment has also been favorable with small numbers of children who have Wiskott-Aldrich syndrome, ...
Mayo Clinic, Rochester, MN; Memorial Sloan-Kettering Cancer Center, New York, NY. Background: Phosphaturic mesenchymal tumors (PMT) are extraordinarily rare mesenchymal tumors, which can cause tumor-induced osteomalacia (TIO) through production of phosphaturic hormones, most often fibroblast growth ...
Multiple Myeloma (MM) is a hematological cancer caused by abnormal plasma cell expansion in the bone marrow (BM)1. MM is preceded by the monoclonal gammopathy of undetermined significance (MGUS); characterized by an abnormal increase in monoclonal immunoglobulin secretion2,3. Progression of the dise...
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Clonal cytogenetic abnormalities are found in the bone marrow cells of 40 to 60% of patients with myelodysplastic syndromes (MDS). We have occasionally observed patients with morphologically normal bone marrow as...
waldenstr枚m macroglobulinemia (wm) is a distinct b-cell subtype of non-hodgkin lymphoma (nhl) characterized by lymphoplasmacytic infiltration of the bone marrow and a monoclonal igm protein. patients often present initially with nonspecific symptoms. the most common symptoms are fatigue and malaise...
Renner C, Hegenbarth U, Schneider JP, Meixensberger J: Fatal bihemispheric intracerebral hemorrhage after burrhole evacuation of chronic subdural hematoma in a bone marrow- transplanted patient: case report and review of the literature. Surg Neurol 2004, 62(3): 260-3; Discussion 263...
Journal of Cancer Research and Clinical Oncology(2023) Diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a refined classification from the European society for blood and marrow transplantation (EBMT) ...
For example, the entity known as smoldering multiple myeloma (SMM), which is a more advanced pre-cursor disorder to MM than MGUS, is a disease state wherein patients do not have any clinical symptoms of MM but have a higher amount of clonal PCs in their bone marrow (>10% but less ...