such as tissue formation, cancer development, diabetes, neurodegenerative diseases, and cardiovascular diseases. Recently, it has been reported that microRNAs can modulate the differentiation and activities of osteoblasts
The cover of this textbook bears an artist’s rendering of a tumor microenvironment in which tumor-associated macrophages (TAMs) have infiltrated among the cancer cells. These TAMs are derived from “myeloid-derived suppressor cells” (MDSCs), which are bone marrow-derived myeloid progenitors that...
With the development of medical knowledge and people's health more and more attention,and many new theories,new knowledge about cancer diagnosis and treatment of constantly emerging,make tumor clinical experience and innovation for the development of more quickly,some unusual diseases have been known,...
DaCosta.Transplantation of bone marrow mononuclear cells decreases seizure incidence, mitigates neuronal loss and modulates pro-inflammatory cytokine production in epileptic rats[J]. Neurobiology of Disease .2011(2)Costa-Ferro ZSM, Souza BSF, Leal MMT, Kaneto CM, Azevedo CM, Da Silva IC et al (...
Cancer. 2013;119:978–85. PubMed Google Scholar Chang YJ, Huang XJ. Use of G-CSF-stimulated marrow in allogeneic hematopoietic stem cell transplantation settings: a comprehensive review. Clin Transplant. 2011;25:13–23. CAS PubMed Google Scholar Shulman HM, Sullivan KM, Weiden PL, Mc...
Cancer. 2013;119:978–85. PubMed Google Scholar Chang YJ, Huang XJ. Use of G-CSF-stimulated marrow in allogeneic hematopoietic stem cell transplantation settings: a comprehensive review. Clin Transplant. 2011;25:13–23. CAS PubMed Google Scholar Shulman HM, Sullivan KM, Weiden PL, Mc...
(b) RVSP and media thickness in irradiated WT recipients of either WT or Thbs1 À / À bone marrow (BM), followed by no treatment or Schistosoma exposure (n ¼ 10, 7 and 7 mice/group, respectively; ANOVA Po0.001 for both RVSP and media thickness, with post hoc Tukey tests shown...
Osteosarcoma, with poor survival after metastasis, is considered the most common primary bone cancer in adolescents. Notwithstanding the efforts of researchers, its five-year survival rate has only shown limited improvement, suggesting that existing ther
Patients with primary and bone metastatic breast cancer have significantly reduced survival and life quality. Due to the poor drug delivery efficiency of anti-metastasis therapy and the limited response rate of immunotherapy for breast cancer, effective treatment remains a formidable challenge. In this ...
Interestingly, mir-17–92-deficiency in B cells leads to enhanced homing of plasma cells to the bone marrow during T-cell-dependent immune response and selectively impairs IgG2c production. Mechanistically, mir-17–92 directly represses the expression of Sphingosine 1-phosphate receptor 1 and ...