However, it is not known whether this association is caused by ongoing bone loss or by lower bone mass earlier in life. To determine whether rate of bone loss is associated with total and cause-specific mortality, we prospectively studied 6046 women aged 65 years or older who had serial ...
Osteoclasts (OCs) are another crucial modulator of bone metabolic homeostasis. On the one hand, osteoclast-mediated bone resorption is an important mechanism of bone loss diseases such as osteoporosis [44,45]. On the other hand, the microenvironment formed by the OCs attachment site in bone tissu...
Pulpitisis inflammation of the pulp of the tooth and may also result inalveolar bone loss. It can result from trauma to the tooth, but most often reflects invasion of dental caries into the pulp chamber. If inflammatory products exit the pulp canal, they can produce a local inflammatory reac...
Early identification of clinical risk factors is essential for the prevention and treatment of the disease3,4. Osteoporosis is a chronic disease characterized by bone loss and microarchitecture impairment. Osteoporosis is diagnosed and monitored mainly by the measurement of bone mineral density (BMD) ...
is primarily caused by abnormal calcium metabolism. Nevertheless, an increasing number of clinical studies, particularly studies on menopausal women, have convincingly shown that excessive iron is associated with osteoporosis. Iron overload has been linked to bone loss and closely associated with ...
reported that loss of PIEZO1/2 results in severe bone defects, while the loss of PIEZO2 alone has only a subtle impact on bone; this finding suggests that PIEZO1, but not PIEZO2, is critical for perceiving mechanical forces in bone.125 In osteoblastic cells, PIEZO1/2 activates Ca2+ ...
In certain diseases (e.g., osteoporosis) and with age, the resorption exceeds formation, resulting in an overall loss of bone. Bone turnover occurs in discrete, focal areas involving groups of cells called bone remodeling or basic multicellular units. The sequence of events at these temporary ...
is primarily caused by abnormal calcium metabolism. Nevertheless, an increasing number of clinical studies, particularly studies on menopausal women, have convincingly shown that excessive iron is associated with osteoporosis. Iron overload has been linked to bone loss and closely associated with ...
Influence of implant geometry on primary insertion stability and simulated peri-implant bone loss: an in vitro study using resonance frequency analysis and damping capacity assessment Int J Oral Maxillofac Implants, 26 (2011), pp. 347-355 View in ScopusGoogle Scholar 29 I. Turkyilmaz, O. Ozan,...
increased bone loss leads to reduced mass and undermined structure of bone, which is frequently called osteoporosis.15Osteoporosis is a systemic bone degenerative disease characterized by progressive loss of bone mass and significant degradation of bone mechanical properties, which subsequently leads to bon...