Bone tissue, or osseous tissue, is a type of connective tissue used in forming bones. Bones protect the vital organs and help support the body. It is composed mainly of collagen, or ossein, fibers, and bone cells called osteocytes. There are two types of bone tissue, referred to as ...
Bone is a tissue composed of organic (cells and matrix) and inorganic (mineral) components. When the mechanical strength of bone is exceeded, fracture occurs. Healing progresses through inflammatory, reparative, and remodeling phases similar to other tissues, but, unlike other tissues, bone ...
Medullary bone is a special bone tissue forming on the endosteal surface of the medullary cavity in the bones of female birds prior to and during egg-laying to serve as a calcium reservoir for building the hard eggshell. It has also been identified in non-avian dinosaurs, where its presence...
Bone-type tissue-nonspecific alkaline phosphatase (TNAP) hydrolyzes inorganic pyrophosphate (PPi) and generates inorganic phosphate (Pi), which is essential for MV-mediated hydroxyapatite formation. MVs contain another phosphatase, PHOSPHO1, that serves as an additional supplier of Pi. Activation of ...
entering a renal dialysis program and given tetracycline bone labels prior to 11th rib biopsy, tissue-level bone formation rates measured by quantitive histological analysis fell below normal in each case and on both the haversian and cortical–endosteal bone surfaces, averaging one-third of normal....
Osteoporosis is characterised by low bone mass and structural deterioration of bone tissue, resulting in increased fragility and susceptibility to fracture. Osteoporotic fractures are a significant cause of morbidity and mortality. Direct medical costs f
Bone is a dynamic tissue, which undergoes continuous remodeling throughout life. Bone homeostasis is maintained by a balance between osteoclastic bone resorption and osteoblastic bone formation1. However, the homeostasis shifts out of balance during aging, resulting in decreased bone formation relative ...
What is the major cell type of a bone? Which layer of protective connective tissue is the outermost covering surrounding a spinal nerve? What is the material within the spaces of spongy bone at the end of the humerus? a. Hyaline cartilage b. Articular cartilage c. Adipose tissue d. Red ...
Background: Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue sarcoma with distinctive histology and uncertain histogenesis, characterized by EWSR1-NR4A3 fusion in 75% of the cases. A smaller proportion of cases show NR4A3 fused to other gene partners including TAF15, TCF12 and ...
Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via a balance between bone formation by osteoblasts and resorption by osteoclasts. These opposite processes allow the accommodation of bones to dynamic mechanical forces, altering bone mass in response to changin...