Monitoring of the first stages of bone healing with microdialysis. Acta Orthop 2013;84:76-81.Y. Fo¨rster, W. Gao, A. Demmrich, U. Hempel, L. C. Hofbauer, and S. Rammelt, "Monitoring of the first stages of bone healing with microdialysis," Acta Orthopaedica, vol. 84, no. 1, ...
When a fracture occurs, a bone becomes unstable and can move back and forth creating a painful phenomenon known as micromotion. As the bone begins healing it must progress through specific, well-defined stages. First, osteoclasts - cells that can break down bone - clean up any fragments or ...
Each stage of the fracture healing process brings with it increased nutritional demands. For starters, the whole process requires a great deal of energy—which is generally supplied through the intake of calories in food. Next, healing requires the synthesis of new proteins, which is dependent upo...
fibroblast growth factors family and 4 fibroblast growth factor receptors (FGFRs) being identified and are found secreted by monocytes, macrophages, mesenchymal stem cells, osteoblasts and chondrocytes, starting from the early stages of fracture healing and lasting throughout the whole healing process [...
Bone healing and osteoporosis A correct fracture healing depends on the synergy between biomechanical, molecular and cellular factors. Focusing on different stages, fracture hematoma re... U Tarantino,I Cerocchi,A Scialdoni,... - 《Aging Clinical & Experimental Research》 被引量: 66发表: 2011年 ...
RESULTS. Although bone repair in general had similar bone healing stages in all the groups, the repair process depended on the mode and degree of injury thus being different in the experimental groups. After the internal fracture, indirect ossification was observed; after osteotomy, primary ...
“M2-like” macrophages in the later stages of bone healing40,41,42are both critically required for proper bone regeneration. The macrophages in contact with the bone paste expressed lowerIL-12and higherIL-10mRNA levels than those in contact with the particular bone graft. This result supports ...
Non-steroidal anti-inflammatory drugs, cyclooxygenase-2 and the bone healing process. Basic Clin. Pharm. Toxicol. 102, 10–14 (2008). CAS Google Scholar Moseychuk, O. et al. Inhibition of CK2 binding to BMPRIa induces C2C12 differentiation into osteoblasts and adipocytes. J. Cell Commun. ...
In addition to assigning bone turnover markers specifically to the process of bone resorption or bone formation, certain markers appear to reflect different stages of these cellular activities. On the other hand, bone turnover markers cannot distinguish between diseases nor do they reflect disease-spe...
As research proceeds, the results of an increasing number of in vitro and in vivo studies illustrate the necessary interactions between bone regeneration and polarized macrophages during the bone healing process. Macrophages, as an essential factor in the regulation of bone homeostasis, may be a ...