Bone growth in length occurs by interstitial growth of the cartilage of the epiphyseal plate, whereas bone growth in width is accomplished by appositional growth occurring deep to the periosteum. Osteoblasts derived from osteoprogenitor cells of the periosteum secrete bone matrix on the bone surface,...
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Growth in long bones occurs at the epiphyseal growth plate (EGP) next to the metaphysis in a process called endochondral ossification. Chondrocyte proliferation, hypertrophy, and apoptosis in the EGP depend on several factors such as genetics, nutrition, environment, and hormones, which influence endo...
Bone growth in length occurs by mitosis of A) cartilage cells in the diaphyseal side of the metaphysis. B) growth of trabeculae. C) cartilage cells in the epiphyseal side of the metaphysis. D) osteoblasts in the endosteum. E) concentric lamellae. ...
Bone development is the formation and growth of bones. New bone is formed by the action of specialised cells called osteoblasts and osteoclasts, either by directly laying down bone tissue into connective tissue or forming it from cartilage, such as during growth in length of long bones. Latest...
Simultaneously, bone is being destroyed along the endosteal surface, at focal points along the periosteal surface, and within the osteons of compact bone. Because bones increase greatly in length and thickness during growth, bone formation occurs at a much greater rate than bone resorption. This ...
The average length of stay in an acute care hospital after a hip fracture is 3 weeks; one in four patients remain in long-term care institutions for at least 1 year; one in three returns home, but must depend on other people or devices for mobility. Further, after a hip fracture there...
Evidence has shown that irradiation alters the degree of cross-linking within the collagen [28]. This occurs as a result of side chain decarboxylation of the collagen molecule, thus modifying the interaction or binding between the organic matrix and the HA mineral [29, 30]. Indeed, the ...
The trabecular volume of interest was located 0.5 mm below the growth plate and extended 2 mm down. MicroCT analyses were also performed on left femurs ex vivo with a Skyscan 1076 microtomograph (Bruker-Skyscan) operated at 50 kV, 200 μA, 2000 ms integration time. The ...
Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via a balance between bone formation by osteoblasts and resorption by osteoclasts. These opposite processes allow the accommodation of bones to dynamic mechanical f