Define bone formation. bone formation synonyms, bone formation pronunciation, bone formation translation, English dictionary definition of bone formation. n. 1. a. The dense, semirigid, porous, calcified connective tissue forming the major portion of the
Bone development is the formation and growth of bones. New bone is formed by the action of specialised cells called osteoblasts and osteoclasts, either by directly laying down bone tissue into connective tissue or forming it from cartilage, such as during growth in length of long bones. Latest...
Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via a balance between bone formation by osteoblasts and resorption by osteoclasts. These opposite processes allow the accommodation of bones to dynamic mechanical f
Bone is a structural tissue and, in common with all structural materials, is subject to fatigue damage. Unique to the skeleton is the ability to self-repair and minimize the risk of fatigue damage. The process is known as eitherbone turnoverorbone remodeling.Once peak adult bone mass has be...
Hypoxia is a major stimulator of osteoclast formation and bone resorption Top of pageMATERIALS AND METHODS RESULTS DISCUSSION LITERATURE CITED Hypoxia is known to act as a general stimulator of cells derived from marrow precursor... TR Arnett,DC Gibbons,JC Utting,... - 《Journal of Cellular Phys...
Currently, mineral substitutes may confer osteoconduction, whereas allograft demineralized bone matrix is purported to exhibit osteoinductive capabilities. New bone formation, osteogenesis, as a discrete entity requires cellular activity. Bone substitutes to date are not osteogenic, since they lack the ...
While later in life, due to the formation of SOC which alters the local microenvironment, a stem cell niche is progressively created in the growth plate. PTHrP/PTHLH, a protein member of the parathyroid hormone family, was discovered as a marker for SSCs residing at the borderline chondrocytes...
The pore size of porous structures directly affects the transport and exchange of nutrients and blood, cell adhesion and proliferation, cell interaction, and even bone formation, so whether the pore size is suitable is an important index for judging porous structures. However, in the existing ...
As natural biomolecules, proteins are naturally secreted from organisms and possess special osteogenic functions [124]. In the process of bone defect repair, the formation of blood vessels, nerves, the osteogenic differentiation of stem cells and even the regulation of the M2-type polarization of im...
3Osteoclast precursors fuse and form a mature osteoclast that is capable of removing damaged tissue via acidic and proteolytic digestion, a process known as bone resorption. This process not only clears out the old bone but also liberates various growth factors from the bone matrix (e.g., Tgf...