and shape as it grows to adult proportions. While the osteoclasts resorb bone at various sites, other cells calledosteoblastsmake new bone to maintain the skeletal structure. During childhood,bone formationoutpaces destruction as growth proceeds. After skeletal maturity is reached, the two processes ...
摘要: Bone growth factors are used to stimulate new bone formation when administered with agents that inhibit bone resorption. These therapeutic combinations result in an enhanced rate of bone formation with an increase in bone mass.收藏 引用 批量引用 报错 分享 文库来源 其他来源 求助全文 Bone ...
and removal are ongoing Function of Bones Blood cell formation Hematopoiesis occurs within the red marrow cavities of the long bones The yellow marrow cavities are involved in fat storage CLASSIFICATION OF BONE SECTION III Classification of Bone: Bones vary in shape and size The unique shape of ...
However, the effects of gut microbiota on skeletal growth and homeostasis have only recently begun to be explored. Here, we report that colonization of sexually mature germ-free (GF) mice with conventional specific pathogen-free (SPF) gut microbiota increases both bone formation and resorption, ...
* * Gerneral principles Periosteal 骨膜的 reactive new bone formation results when the tumor destroys cortex 皮质 and may take the form of a Codman‘s triangle, “onion-skinning 透明片,” or a “sunburst 炎爆 pattern. It usually is a sign of malignancy but may be present with infection or...
For teratoma formation assay, single-cell suspension of cultured ESCs in PBS (4 × 106 cells in 100 μl PBS) was subcutaneously injected into the flanks of immunodeficient RAG2?/?gc?/? mice. After 4–7 weeks, teratomas were excised, fixed, and subjected to histological analysis. 63 p...
The HIF signaling pathway enhances bone formation and bone immunity by regulating immune cell activity, important pathways, and important secretory molecules. Bone immunology includes the molecular and cellular interactions between osteoblasts, osteoclasts, lymphocytes, and hematopoietic cells [58,59,60]. ...
Autologous bone has no particular disadvantages other than restrictions on the collection amount and collection site and is recognized as a good prosthetic material with new bone formation capacity. It is thus considered the current gold standard for the regeneration of bone defects but has been most...
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Surgical reattachment of tendon and bone such as in rotator cuff repair, patellar-patella tendon repair and anterior cruciate ligament (ACL) reconstruction often fails due to the failure of regeneration of the specialized tissue ("enthesis") which connec