There were six groups +/- PE/cPE and +/- treatment with MSCs or pMSCs (7-9 mice/group). MicroCT analysis was carried out 6 weeks after primary surgery. A three-dimensional region of interest (ROI: 4 脳 4 脳 3 mm) was created in the distal femur. Bone mineral density (BMD, mg...
These findings may provide a new pathological mechanism for related metabolic diseases or be used in the diagnosis, treatment, and prevention of metabolic diseases such as osteoporosis, obesity, and diabetes mellitus. In this review, we summarize the regulatory effect of bone and bone-derived ...
satiety, and are also responsible for the central regulation of bone density and layered features. Central neuronal regulation of bone occurs through hormonal signals produced by hypothalamic neuroendocrine neurons, which are responded to by the pituitary...
Bone mineral density and body composition before and during treatment with gonadotropin-releasing hormone agonist in children with central precocious and e... Major changes in bone mineral density (BMD) and body composition occur during puberty. In the present longitudinal study, we evaluated BMD and...
Mesenchymal stem cell-based therapy has become an effective therapeutic approach for bone regeneration. However, there are still limitations in successful clinical translation. Recently, the secretome of mesenchymal stem cells, especially exosome, plays
Bone density (BMD) and bone volume/total volume (BV/TV) in the defect area were quantitatively analyzed from the micro-CT images. CTAn software (version: 1.17.7.2) was used to reconstruct the region of interest, and the bone quality was observed using CTvox software. 2.15. In vivo blood ...
In addition, the low signal intensity on T2-weighted images and DW images of benign bone lesions, such as non-ossifying fibromas and osteofibrous dysplasia tumors, may have been due to the high density of fibers, low cellularity, and low water content in both the extracellular and ...
Proliferation of 66cl4pBabe and 66cl4beta3 cells was measured over 5 days in complete α-MEM medium with an initial cell density of 1 × 103/well and five replicate wells/time point. Adhesion assays were performed in 96-well culture plates as described previously [44]. Briefly, triplicate ...
Osteoporosis is a global health problem for ageing populations. The goals of osteoporosis treatment are to improve bone mineral density (BMD) and prevent fractures. One major obstacle that remains a great challenge to achieve the goals is how to select t
In the traditional treatment group, the blasting group exhibited the highest absorbance, with an optical density (OD) value of approximately 1.3 on the 7th day. In the 3D-printed group, EBM was significantly stronger than SLM, with an OD value of approximately 0.8 for PT-SLM and 1.1 for ...