Recent evidence demonstrates that bisphosphonates increases bone mineral density (BMD) in the vast majority of patients, so that routine monitoring after initiation of bisphosphonates is not be warranted. Investigators performed a secondary analysis of data from the Fracture Intervention Trial using a mixe...
Regional variation in the denial of reimbursement for bone mineral density testing among US Medicare beneficiaries. J Clin Densitom 2008;11:568-74.Curtis JR, Laster AJ, Becker DJ, et al. Regional variation in the denial of reimbursement for bone mineral density testing among US Medicare ...
According to OrthoFix, the CervicalStim device is the only bone growth stimulation therapy approved by the (FDA as a non-invasive, adjunctive therapeutic option for cervical fusion in patients at high-risk for non-fusion. The device uses a pulsed electromagnetic field (PEMF) to induce a low-le...
Effects of long-term treatment of denosumab on bone mineral density: insights from an in-silico model of bone mineralization. Bone. 2019;125:87–95. https://doi.org/10.1016/j.bone.2019.04.022. Article CAS PubMed Google Scholar Gibiansky L, Sutjandra L, Doshi S, et al. Population ...
Interestingly, newly formed bone is disorganized, typically with low density, and is weak in strength [114,115]. This is due to a malalignment of osteoblasts along a collagen matrix, leading to the production of bone with a spongy structure as opposed to a hard and compact l...
histomorphometry of proximal and distal tibiae revealed no differences in adipocyte density or BM adiposity between the three groups (Supplementary Fig.4A–D). Cold exposure also decreased BAT lipid content and promoted beiging of iWAT, as indicated by formation of multilocular adipocytes (Fig.5d,...
A protective effect of UA on bone mineral density (BMD) has been hypothesized because UA is a potent antioxidant in plasma.7 Several observational studies suggest that higher levels of serum UA (sUA) are associated with greater BMD and thus may be a protective factor in osteoporosis.8-11 ...
Here we report the identification of human CD66b−CD64dimCD115− neutrophil-committed progenitor cells (NCPs) within the SSCloCD45dimCD34+ and CD34dim/− subsets in the bone marrow. NCPs were either CD45RA+ or CD45RA−, and in vitro experiments s
Cell cultures were seeded at a density of 1.5 × 104 cells in six-well plates and grown in Low Glucose DMEM medium (EuroClone, Milan, Italy) containing 10% FBS (Euro-Clone, Italy) and 3 ng/mL of b-FGF (Prepotech, London, UK), 1% penicillin/streptomycin (Microgem, Naples, Italy),...
These observations were supported by the histological analysis in terms of the corresponding bone thicknesses (0.75 mm coated vs. 0.47 mm bare titanium), and relative bone mineral density (95% of normal bone) [100]. Based on this, it was demonstrated that priming the bone with a layer-by-...