Currently age-related bone loss is not fully understood. Factors affecting bone density include: hormonal changes in women, physical activity, genetic determination, and peak level of bone mass attained in youth. Loss of bone mass with bed rest, spaceflight, and paralysis all indicate a ...
We have studied a normal adult caucasian population (462 females, 264 males age range 20-84) using dual photon absorptiometry to establish patterns of bone reduction at the spine and hip. Subjects were either randomly selected from the electoral roll or volunteers. Bone mineral density reduction ...
Adipocyte differentiation of bone marrow mesenchymal stem/stromal cells (BMSCs) instead of osteoblast formation contributes to age- and menopause-related marrow adiposity and osteoporosis. Vascular calcification often occurs with osteoporosis, a contradictory association called “calcification paradox”. Here ...
For example, bone remodeling simulations showed that a 10% increase in peak bone mineral density (BMD) would delay osteoporosis by 13 years. Puberty is a key early life milestone that is characterized by endocrine-initiated reproductive maturation and a dramatic skeletal growth spurt in height. 例...
Much of the formation of bones takes place in one's childhood and teen years, so it is important to take in the right nutrients from a young age.Bone density naturally declines as people age. The production of new bones slows down and can't keep up with the rate at which old bones ...
Age-related losses in bone mineral density (BMD), muscle strength, balance, and gait have been linked to an increased risk of falls, fractures and disability, but few prospective studies have compared the timing, rate and pattern of changes in each of these measures in middle-aged and older...
<MissingAbstract>Purpose/Hypothesis: Bone mineral density (BMD) is believed to decline at different rates in women and men. It is not known whether declines in pedal bone density show similar sexual dimorphism. The purpose is to determine the age-related declines in calcaneal BMD in cohorts of...
Introduction: The changes in bone structure and density with aging that lead to fragility fractures are still unclear. Materials and Methods: In an age- and sex-stratified population sample of 373 women and 323 men (age, 20-97 years), we assessed bone geometry and volumetric BMD (vBMD) by...
We constructed age- and sex-smoothed reference values for areal bone mineral density (aBMD) of total body less head (TBLH), total body (TB), lumbar spine (LS), and bone mineral apparent density (BMAD) for LS, by means of Generalized Additive Models for Location, Scale and Shape (...
Bones become thinner and more porous as their density decreases. They tend to lack important minerals, such as calcium, that keep them strong. This greatly increases the chance of breakage; as such, people who are advanced in age must be careful to prevent falling and breaking their thin and...