Bone-Derived IGF Mediates Crosstalk between Bone and Breast Cancer Cells in Bony Metastases Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases. Cancer research. 2012; 72:4238-4249.Hiraga, T., Myoui, A., Hashimoto, N., Sasaki, A., Hata, K., Morita...
Bone cancer is characterized by uncontrolled growth of cells of the bone. Primary bone cancer (that arises directly in the bone), is relatively rare. Different types of bone tissue give rise to different types of primary bone cancer: osteosarcoma develops from cells that form the bone and Ewing...
Finally, we ascertain whether mutations in the RBP-J gene are associated with leukaemia in humans as well. We find that renin is expressed by a subset of B-cell progenitors in the mouse bone marrow, and that these renin-expressing cells are the cell of origin for B-cell leukaemia when ...
Dogs Join Fight against Bone Cancer; FDA-Approved Drugs to Be Tested on Canines with Bone Cancer That Also Affects HumansThompson, Dennis
As stated in several publications, more models for immuno-oncology concentrating on bone metastasis are needed [9, 12, 19]. The aim of this study was to establish the first breast cancer bone growth model in humanized mice. This novel model would then combine the human tumor, bone, and ...
摘要: Explores the efficacy of prostheses in the management of bone cancer. Emphasis on the improvement in the quality of life of the patients; Sites of primary bone tumors; Conduction of a bone scan for preoperative assessment.关键词:
Noteworthily, SOX4 is implicated in other pathologies linked to inflammaging, such as cancer90, cardiovascular diseases91, diabetes92, and arthritis93,94. It will thus be worth assessing the presence of similar changes in these conditions to eventually propose multi-disease therapies. Our data ...
Exposure to ionizing radiation has well-documented long-term effects on cancer rates and other health outcomes in humans. While in vitro experimental studies had demonstrated that the nature of some radiation effects depend on both total dose of the radiation and the dose rate (i.e., the patter...
(Mundy, 1997; Sterling et al., 2011). This results in osteolytic bone destruction, which is common in breast and lung cancer bone metastasis, and observed less often in prostate cancer bone metastases. Many of the primary therapies for bone metastatic breast cancer target osteoclasts in an ...
sickle cell diseasebone painfeveranemialeukoerythroblastic differentialBACKGROUND In the medical community, little is known regarding bone marrow necrosis (BMN)... AM Janssens,FC Offner,WZ Van Hove - 《Cancer》 被引量: 58发表: 2015年 Bone Marrow Necrosis : Report of a Case and a Brief Review...