In this study, pore channels within collagen scaffolds directed cell alignment and ECM fibre orientation, resulting in fibrocartilage, which is progressively mineralized into bone. CAS Google Scholar Guo, J. L. et al. Modular, tissue-specific, and biodegradable hydrogel cross-linkers for tissue ...
However, very recent studies revealed that osteocalcin may participate in the correct parallel alignment of apatite crystals with collagen fibrils (Figure 3) [34] and possibly modulate the composition of the crystal hydrated surface [35]. SIBLING proteins are particularly enriched in charged and polar...
thesuperior and inferior gemelli— twins. In the abdominal wall, alignment is everything. Therectus(straight)abdominis(the highly valued “six-pack”) runs longitudinally, while theobliquus externus abdominisandtransversus
is also released by other peripheral nerves195,196and is mediated by three types of GPCRs (VPAC1, VPAC2, PAC1).196VIP can promote BMSC osteogenic differentiation through the Wnt/β‐catenin signaling pathway in rats.197Although reported to inhibit BMSC proliferation,198VIP-containing MeHA hydroge...
The alignment program, Bowtie2 (v2.3.4.1), was used for mapping reads to the mouse reference genome mm10 and Sambamba (v0.6.7) was used to remove duplicate reads. The algorithm, MACS (in Python v2.7.3), was utilized to call peaks of signal for annotated genomic features. The package...
In subpanel D, alignment of the AP and YFP images shows that the trabecular lining cells co‐express AP and YFP. b, Co‐localization of En1 and alkaline phosphatase expression. Images of lumbar vertebrae sections (growth plate and trabecular bone regions, ×40 magnification) from two‐month ...
In alignment, treatment with bisphosphonates will suppress bone resorption to lower levels than cartilage degradation. Presence and activation of osteoclasts seem to be involved in the pathogenesis of OA and other cartilage degenerative diseases41, 42. Increased expression of osteoclast differentiation ...
Bone spurs, also referred to as Osteophytes are something that can directly affect the likelihood of experiencing back pain. Bone spurs take a while to develop and are found near the disc or joint areas between the spinal vertebrae. This alignment of bones is bound together with cartilage that...
Bowtie2 was employed for alignment and mapping of short sequence reads to the human genome reference hg19 and the fusion transcript SFPQ/PSF-TFE3. Integrative Genomics Viewer (IGV) was employed for data visualization. Results: We identified 3 cases with PSF-TFE3 fusion, one case with FOXO1-...
Fast and accurate short read alignment with Burrows–Wheeler transform. Bioinformatics 25, 1754–1760 (2009). Article CAS PubMed PubMed Central Google Scholar Afgan, E. et al. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update. Nucleic Acids Res. ...