Circulating concentrations of adiponectin, an adipocyte-derived protein, are decreased with insulin resistance. We investigated the relationships between adiponectin and leptin, body fat distribution, insulin sensitivity and lipoproteins. Methods We measured plasma adiponectin, leptin and lipid concentrations, ...
Apparent KD to primary T cells was in the sub-μM range (310 nM to human and 210 nM to cyno T cells), which was substantially higher than the single-targeting controls despite relatively comparable KDs to TCRαβ and CD3 protein respectively (supplemental Table 4). Based on literature,42...
(5) hs-CRP, high sensitivity C-reactive protein (6) No significant difference via paired t-tests at p < 0.05. † Significance was determined using the Wilcoxon signed rank tests, †*p < 0.05. (7) No significant difference via independent t-tests at p < 0.05. † Significance was de...
All three coding positions of protein-coding gene COI were included in the analyses. Best-fitting substitution models were assessed for each locus (partition) under the AIC criterion in jModelTest 2.1.439, the TVM+I+Γ, TPM2uf+I+Γ, GTR+I+Γ and GTR+I+Γ models selected for COI, 16S,...
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...
HOWEVER, one group was given a more balanced diet comprised of meals that contained protein, fat and carbs, while the second group had their carb and fat calories separated so they were not eaten together in the same meal. Guess what happened? They all lost the same amount of weight and ...
Protein secondary structure detection based on surface plasmon resonance of graphene nanowires Optik, Volume 216, 2020, Article 164703 Kai Tong,…, Xiaogang Wu Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress Cancer Cell, Volume 39, Issue...
Protein concentrations were determined by BCA assay and equal amounts of proteins were separated on 4–15% Tris-Glycine eXtended (TGX) polyacrylamide gels. Proteins were transferred onto nitrocellulose membranes (Bio-Rad, Hercules, CA) for IB analyses. The following primary antibodies were employed:...
Mouse anti-Hts-F (1B1 adducin-related protein) (IF 1:50) DSHB RRID: AB_528070 Mouse anti-GFP (IB 1:1000) Sigma-Aldrich Cat#11814460001; RRID: AB_390913 Mouse anti-GAPDH (IB 1:5000) Abcam Cat#ab9484; RRID: AB_307274 Guinea pig anti-ALIX (IB 1:2500, IF 1:2500) [10] RRID: ...
SGs and PBs are cytoplasmic mRNP condensates, whose formation involves protein-RNA interactions, RNA-RNA interactions, prion-like domains (PrLD) and liquid-liquid phase separation [[1], [2], [3]]. PrLD consist of low complexity disordered regions, which compositionally resemble prion domains. ...