Two UK guidelines advocate the measurement of plasma concentrations of B-type natriuretic peptide (BNP) in diagnosis of chronic heart failure, either in combination with, or as an alternative to, an ECG.1,2 Here we review the evidence for BNP testing in the diagnosis of chronic heart failure...
Furthermore, while elevated BNP levels are highly sensitive to heart failure, they are not specific to its cause; elevated BNPs may be seen in various cardiac and noncardiac diseases, as previously mentioned. It is, therefore, neces...
[Abstract] Objective:To study the application of BNP testing in clinical diagnosis of chronic heart failure.Method:110 cases of hospitalized patients with chronic heart failure treated in our hospital in recent years were selected as observation group,at the same time,the same number of patients wi...
They're able to spot heart failure more than 80% of the time. If you already have heart failure, your doctor might also use one of these blood tests to see how your heart is doing and if your condition is getting better, worse, or staying the same. These tests can also help you fi...
BNP Testing in Heart Failure - One Fits All? 来自 ResearchGate 喜欢 0 阅读量: 14 作者: B Stanek 摘要: In patients with cardiac dysfunction natriuretic hormones originating from the ventricles (B-type natriuretic peptide and N-terminal BNP) are abnormally elevated in the peripheral circulation ...
Lainchbury J,et al. NT-proBNP testing fordiagnosis and short-term prognosis in acute destabilized heart failure: aninternational pooled analysis of 1 256 patients: the InternationalCollaborative of NT-proBNP Study [J]. Eur Heart J, 2006 27 ...
Lainchbury J,et al. NT-proBNP testing fordiagnosis and short-term prognosis in acute destabilized heart failure: aninternational pooled analysis of 1 256 patients: the InternationalCollaborative of NT-proBNP Study [J]. Eur Heart J, 2006 27 (3) :330-337. DOI:10. 1093/eurheartj/ehi631....
8. Januzzi JL, van Kimmenade R, Lainchbury J, et al. NT-proBNP testing for diagnosis and short-term prognosis in acute destabilized heart failure: an international pooled ysis of 1256 patients: the International Collaborative of NT-proBNP Study Eur Heart J, 2006,27(3):330-337. ...
ESCGuidelinesforthediagnosisandtreatmentofacuteandchronicheartfailure2012 Cut-offpoint Acuteonsetorworseningofsymptoms NT-proBNP 300pg/mL BNP 100pg/mL MR-proANP 120pmol/L Non-acuteonset 125pg/mL 35pg/mL 在无急性发作的患者中，BNP和NT-proBNP诊断心衰的敏感性和特异性相对较低 NP阈值随年龄增大而增加...
(NT-proBNP) are widely used as biomarkers to diagnose heart failure and assess a patient’s response to therapy. Cardiomyocytes secrete proBNP in response to myocardial wall stretch, which is further cleaved into two circulating fragments; C-terminal B-type NP (BNP), a biologically active ...