CaseinKinase作⽤通路:PROTAC;CellCycle/DNADamage;StemCell/Wnt储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性BMS-986397cereblon的CK1α(酪蛋⽩激酶1α)分⼦胶降解剂,可导致TP53野⽣型AML(急性髓性⽩⾎病)细胞快速凋亡和细胞周期停滞[1]。