farnesyl transferase抑制剂(BMS-214662) 中文名称:farnesyl transferase抑制剂(BMS-214662) 英文名称:BMS-214662 产品规格:1mL(10mM)|1mg|5mg|10mg|25mg|50mg|100mg BMS-214662是有效选择性的farnesyl transferase抑制剂,具有有效地抗肿瘤活性。 注:本品仅可用于科研实验,严禁用于临床医疗及其他用途! CAS号:195987-...
BMS-214662 MESYLATE 反馈纠错 帮助中心 打印 UNII号 CY68RYB4QI 化学名 BMS-214662 MESYLATE 分子式 C25H23N5O2S2.CH4O3S CAS号 474010-58-7 结构式图片 SMILES CS(O)(=O)=O.O=S(=O)(N1CC2=C(C=CC(=C2)C#N)N(CC3=CN=CN3)C[C@H]1CC4=CC=CC=C4)C5=CC=CS5 ...
产品名称:farnesyl transferase抑制剂(BMS-214662) 英文名称:BMS-214662 产品货号:M01729 产品规格:1mL(10mM)|1mg|5mg|10mg|25mg|50mg|100mg BMS-214662是有效选择性的farnesyl transferase抑制剂,具有有效地抗肿瘤活性。 注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!
BMS-214662性质、用途与生产工艺 生物活性 BMS-214662是有效选择性的farnesyl transferase抑制剂,具有有效地抗肿瘤活性。 靶点 IC50: 1.35 nM (farnesyl transferase), 1.3 μM (Ras-CVLL), 2.3 μM (K-Ras) 体外研究 BMS-214662 is over 1000-fold selective for farnesyl transferase, having IC50values for ...
BMS-214662,来源于药化词典-药智数据
BMS-214662 | MedChemExpress 英文名称: 总访问: 43 国产/进口: 进口 半年访问: 6 产地/品牌: Medchemexpress (MCE) 产品类别: 生化试剂 规格: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg 最后更新: 2020-3-10 货号: HY-16111 CAS 号: 195987-41-8 参考报价: 3770; 3500; 6000; 12000 立即询价 ...
BMS-214662 significantly and selectively induced apoptosis in primitive CD34(+)38(-) CML compared with normal cells. Apoptosis proceeded via the intrinsic pathway: Bax conformational changes, loss of mitochondrial membrane potential, generation of reactive oxygen species, release of cytochrome c, and ...
我去年在网上就看到说研制出治疗慢粒的BMS-214662,请问现在是否推出了,如果推出的话又叫什么名,请知道的告诉一声,万分感谢!!! 网友 1 最佳答案 回答者:网友 是一种法x基转移酶抑制剂,可针对静止期细胞信号传导。 还没有上市,没有商品名,Ⅰ期临床试验阶段。推荐...
BMS-214662 was cytotoxic against CML blast crisis stem/progenitor cells, particularly in combination with a tyrosine kinase inhibitor and equally effective in cell lines harboring wild-type vs mutant BCR-ABL, including the T315I mutation. This is the first report of an agent with activity in ...
BMS-214662 potently induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors. Blood. 2008;111:... M Copland,F Pellicano,L Richmond,... - 《Blood》 被引量: 294发表: 2008年 Erratum in Copland et al. BMS-214662 potently induces apopt...