.10 The highly conserved canonical TGF-b/BMP linear signaling cascade engages the TGF-b/BMP ligands, two cell surface BMP receptors (BMPRs), and signal transducers, Smads.11 1Tissue Banking and Biomaterial Research Unit, Atomic Energy Research Establishment, Dhaka 1349, Bangladesh and 2Lab of ...
Notch signaling pathway and TGF-β/BMP signaling In the nucleus, Notch ICD (intracellular domain) binds specific transcription factors and recruits transcriptional co-activators to induce the expression of bHLH family of genes.152Notch pathway is active in the early stages of osteoblast differentiation,...