Whole blood is about 4.5-5.5 times as viscous as water, indicating that it is more resistant to flow than water. This viscosity is vital to the function of blood because if blood flows too easily or with too much resistance, it can strain the heart and lead to severe cardiovascular problem...
In the CTR dogs, myocardial blood flow increased in direct relation to cardiac work. However, in the CKD dogs (stage 1 and 2), maximum blood flow was achieved with low-dose dobutamine, indicating that coronary autoregulation is more readily exhausted with minimal increases in cardiac work ...
Besides, the pro-oxidant and antioxidant activities of patients in distinct stages of chronic kidney disease are divergent, while hemodialysis patients have the most impaired renal function. Consequently, they have the highest amount of oxidative stress, which contributes to the elevation of serum ...
Data from the UK PAH Cohort study are available upon reasonable request to the access committee cohortcoordination@medschl.cam.ac.uk. The use of the Materials or Data must be for research projects and work that falls under the remit of the National Cohort Study of Idiopathic and Heritable PAH...
which is because the blood stasis in the interior blocksQi, so thatQican not raiseJin, it is named as blood thirst, and the thirst will not disappear until the blood stasis is removed, indicating that blood stasis is associated with DM [58]. Blood stasis syndrome is characterized by fixed...
In this work, a nine-emitter implantable device, SonoCloud-9 (SC9, Carthera, Lyon, France), was developed to disrupt a much larger region of the peritumoral brain than tested in the FIH study for drug delivery and evaluated in a Phase I/II multicenter clinical trial in rGBM patients ...
Unfortunately, previous work had demonstrated that platelets adhere to the PNIPAAm surface above the LCST, while platelet adhesion is inhibited below the LCST. This is a problem since at body temperature, the polymer would cause accumulation of platelets and thus cause blood coagulation and ...
29,31,33-35 Mandating medication reduction in this trial, while ensuring all participants continued some antihypertensive treatment, may have reduced clinical inertia by the treating physician compared with previous work.36,37 The only other trial that has examined the effect of antihypertensive ...
Since the discovery of metal nanoparticles (NPs) in the 1960s, unknown toxicity, cost and the ethical hurdles of research in humans have hindered the translation of these NPs to clinical use. In this work, we demonstrate that Pt NPs with protein coronas
and why the human body mounts immunological responses to these antigens. Clearly, much more work remains to be dome to unravel the causes of alloimmunization. With this knowledge and understanding, the blood bank community can continue to improve the safety and compatibility of transfusion therapy....