The first three functions listed above refer to important haemostatic mechanisms in which platelets play a role in during bleeding: vascular spasms, platelet plug formation and blood clotting (coagulation). Vascular spasm This is a prompt constriction of the broken blood vessel and is the most immed...
Developmental biologyThe article focuses on research regarding the mutation in the Alk2 gene of patients with fibrodysplasia ossificans progressiva (FOP), which results to the formation of bone in soft tissues and the endothelial cells.doi:10.1038/468479aA. Biffi...
Blood is carried through the body via blood vessels. An artery is a blood vessel that carries blood away from the heart, where it branches into ever-smaller vessels. Eventually, the smallest arteries, vessels called arterioles, further branch into tiny capillaries, where nutrients and wastes are ...
A new technique of measuring blood vessel volume in bone applied to the mandible and humerus of the rat. Anat. Rec. 1971; 170 :143–146.Brady, J.M. & Cutright, D.E. A new technique of measuring blood vessel volume in bone applied to the mandible and humerus of the rat. Anat. ...
In subject area: Biochemistry, Genetics and Molecular Biology Vascular tone is maintained by constriction or relaxation of vascular smooth cells (SMCs) under control of a monolayer of endothelial cells (ECs) that form a physical barrier between the vessel and the circulating blood. ...
Recently, the synergy between nanoscience and tissue engineering has led to great developments in biomedical research, as well as clinical practices, including the realms of bone and cartilage regeneration, blood vessel tissue engineering, wound dressing, etc. (Wen et al., 2005). In the body, ...
This may be due in part to the direct effects of hypoxia, which blocks osteoblast function and bone formation but causes reciprocal increases in osteoclastogenesis and bone resorption. Common regulatory factors such as parathyroid hormone or nitrates, both of which are potent vasodilators, might ...
Abnormalities in tumor blood vessel function and architecture result in abnormal blood flow [9,11,12]. This combined with the lack of lymph drainage of tumor tissue results in high interstitial pressure in tumors and poor access to the majority of tumor cells [10,11]. In contrast to the ...
Bone Marrow and Blood Cells Structure and Function, 724 Dysfunction/Responses to Injury, 730 Portals of Entry/Pathways of Spread, 744 Defense Mechanisms/Barrier Systems, 744 Disorders of Domestic Animals, 744 Disorders of Horses, 758 Disorders of Ruminants (Cattle, Sheep, and Goats), 758 Disorders...
Ovarian function declines significantly as females enter middle-age, but the mechanisms underlying this decline remain unclear. Here, we utilize whole-organ imaging to observe a notable decrease in ovarian blood vessel (oBV) density and angiogenesis intensity of middle-aged mice. This leads to a di...