Prior to human transplantation application, clarification and elucidation of the pig organ compatibility with the human host thromboregulation system are prerequisite in the pig-to-human or pig-to-primate xenotransplantation. Pig xenografts promote inten
Blood types are determined by antigens found in red blood cells. Learn about the blood types, red blood cell antigens, agglutination, the ABO system, the blood groups, and the definitions of universal donor and universal recipient blood types. ...
of tissue. The application of this technology to monitor liver oxygenation has been validated in models of endotoxicshockin pigs (Nahum et al, 2006) and by intraoperative quantification of congestion and mitochondrial redox duringHV occlusionin living-donor transplantation (Ohdan et al, 2003)....
b Lollipop chart showing the top ten scoring proteins in each cancer model, with the exception of myeloma with only nine positive proteins. c Selected examples of upregulated proteins for each of the cancer types. The colored boxes indicate the cancer type where the protein is upregulated, and...
Primary brain capillary endothelial cells (BCECs) are a promising tool to study the blood–brain barrier (BBB) in vitro, as they maintain many important characteristics of the BBB in vivo, especially when co-cultured with pericytes and/or astrocytes. A novel strategy for drug delivery to the ...
Samples from the included datasets consisted of patients with a diagnosis of possible or probable AD and cognitively normal controls at the time of assessment (Table 1). Donor age (ranging from 72 to 79 years old) and sex were generally well matched, both across and within datasets (Table 1...
Figure 1. Validation of DNA damage response and repair kinetics analyses. (A,B) Following irradiation (2 Gy), immortalized lymphoblastoid cells (LCLs) and healthy donor peripheral blood lymphocytes (PBLs) showed an increase in double-strand break (DSB) marker foci at +1 h (i.e., DNA damag...
Assessment of minimal residual disease (MRD) is the most powerful predictor of outcome in B-type acute lymphoblastic leukemia (B-ALL). MRD, defined as the presence of leukemic cells in the blood or bone marrow, is used for the evaluation of therapy efficacy. We report on a microfluidic-base...
After isolation, plasma was aliquoted and immediately stored at −80 °C until analysis. A total of 396 plasma specimens were obtained from 51 control donors and 175 lung cancer patients. Only one specimen per control donor was collected (total of 51 control specimens), whereas one or more ...
Focusing on blood units stored for a short vs. long duration,Figure 2shows the results of this type of comparison of storage time effects on the flux PK for each individual donor as an example. For each donor, the weekly averaged storage time effects during Weeks 2–6 were compared against...