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When analyzing the near and distant motifs for sex hormones, we suggested that: (1) the differential methylation found in CpG sites could interfere with the binding in motifs close to TSS of transcriptional factors classically related to females and males and; (2) other factors that are not ex...
Patients were assigned to the COVID- 19 group only after receiving a positive test result via nasopharyngeal swab testing using the Abbott Realtime SARS-CoV-2 Assay® (Abbott, IL). SARS-CoV-2 test nega- tive participants were assigned to the non-COVID-19 res- piratory patient group as...
Toxicities which affect the cardiovascular system (i.e. the heart, blood vessels and blood constituents) are a relatively frequent finding during the non-clinical safety testing of candidate drugs in animals, and are an important cause of human ADRs detected during clinical trials or post-licensing...
Superiority of home blood pressure measurements over office measurements for testing antihypertensive drugs. Blood Press Monit 1998; 3: 107–114. 55 Ragot S, Genes N, Vaur L, Herpin D. Comparison of three blood pressure measurement methods for the evaluation of two antihypertensive drugs: ...
Modern medicine emphasizes the concept of homeostasis, constancy of the intern milieu. Accordingly, it is assumed that biological functions and processes are relatively stable during the 24 h and other time periods and that the exacerbation of disease an
(CNLOH) events detected in a subset of cells1. In high-income countries, mCAs are detected in 0.2–1.0% of children undergoing clinical genetic testing for developmental disorders2, but population-based investigations indicate a sharp increase in mCAs frequency in adults, from ~2% in individuals...
He noted that an analysis of patients enrolled in the Intergroupe Francophone du Myelome (IFM) 2009 study has shown a subgroup of patients for whom PET/CT remains positive after treatment but MRD testing is negative, which is likely a consequence of not sampling an area of residual disease....
A blood testing apparatus has a test member and a laser source configured to produce a wound from which blood flows. The laser source produces at least a cutting wavelength, and a c