People over age 60 may have an apparently normal creatinine blood level but still have a low GFR. The opposite can also be true, where the person may have a mildly low GFR without having kidney disease. The 24-hour urine collection method or another blood test called cystatin C can more ...
AstraZeneca
Results Patient characteristics All 95 patients received anti-PD-1/PD-L1 inhibitor treatment. The patient characteristics are summarized in Table 1. The median age was 62 years (range, 30–80 years); most patients (64.2%) exhibited an ECOG PS of 1. First-line and second-line treatments with...
“I wouldn’t worry now,” she said, but she suggested that I get retested in three months to see whether the results were still out of the normal range. The low eGFR number and high creatinine level could signal a kidney problem, she said, or they could mean...
Results Patient characteristics All 95 patients received anti-PD-1/PD-L1 inhibitor treatment. The patient characteristics are summarized in Table 1. The median age was 62 years (range, 30–80 years); most patients (64.2%) exhibited an ECOG PS of 1. First-line and second-line treatments with...
In this regard, the severity of AKI [47, 48] and the baseline eGFR [49] in the group non PI-BUN/Cr & AKI were critical factors that could impact in the prognosis and survival of this patients. This differentiation based on PI-BUN/Cr is similar in some results to that described by ...
However, epidermal growth factor receptor (EGFR), an affinity receptor of AREG, was predominantly expressed in tumor-derived endothelial cells rather than normal37. Thus, the underlying mechanism by which AREG acts on endothelial cells remains to be further investigated. In additional, it is to ...
We hypothesized that the reduction in neutrophil apoptosis results from their increased pro-inflammatory responses. We examined neutrophil activation and generation of reactive oxygen species (ROS) at an earlier time point (4.5 h post-treatment) that is within the normal range of neutrophil half-...
144,145 Inhibition of the activity of these receptors results in the suppression of downstream oncogenic signaling cascades including those engaging mitogen-activated protein kinase and phosphatidylinositol-3-kinase.146 Dp strongly inhibited the protein tyrosine kinase activity of all tested RTKs (EGFR, ...
For the management of hypertension in middle-aged and elder people, long-term effectiveness is as important as lowering the elevated blood pressure to within the normal range. The aim of blood pressure control is to reduce the risk for cardiovascular and cerebro- vascular events and all-cause ...