DNA methylation (DNAme) is the most widely studied type of epigenetic mark. In humans, most DNAme comprises the addition of a methyl group to cytosine bases within cytosine-guanine (CpG) DNA sequences, usually concentrated in relatively high densities, referred to as CpG islands. Alterations in ...
Walk through that door and you might as well be in Port Merion, you're just an effing number. No such thing as jut turning up these days, you are now encouraged to book appointments. On arriving at the donation centre you are met by a phalanx of NHS regulation, handgel and the in...
NHS trust: our experience J Gururaj1 and S Thomas1 1Haematology Outpatient Department, Catherine Lewis Centre, Hammersmith Hospital, Imperial College Healthcare NHS Trust Multiple sclerosis (MS) is an auto-immune condition where the immune system attacks the myelin sheath, causing a varied array of...
Six cognitive phenotypes were assessed in this study: logical memory, digit symbol test score, verbal fluency, vocabulary, general cognitive ability, and general fluid cognitive ability. The logical memory phenotype (verbal declarative memory) was calculated from the Wechsler Logical Memory test, taking...
Activated neutrophils produce neutrophil-derived microvesicles (NMV), which are internalised by human brain microvascular endothelial cells and increase their permeability in vitro, suggesting that NMV play a role in blood–brain barrier (BBB) integrity during infection. The current study investigated ...