The hypergeometric test was applied to assess the degree of overlap of pleiotropic gene candidates (positional) among all genes annotated with the given term, and considering all protein-coding human orthologs as background. The Locus Overlap Analysis (LOLA; R version 1.28.0) [53] was applied ...
Abbreviations TBI: Traumatic brain injury XFZYD: Xuefu Zhuyu decoction HSYA: Hydroxysafflor yellow A mNSS: Modified Neurologic Severity Score TUNEL: TdT-mediated dUTP nick end labeling FITC: Fluorescein isothiocyanate ECs: Endothelial cells SPF: Specific pathogen-free GABA: Gamma-...
Overall, the differentially expressed transcripts found in whole blood describe a downregulation of TH1 differentiation and cell-mediated immunity. For a list of gene/protein abbreviations and their official HUGO names, please see Additional file 4. The squared correlation coefficient of RNA transcript ...
Malignant blood disorders depend on heritable susceptibility genes and occur in familial aggregations. We suggest a model of transgenerational segregation of the susceptibility genes based on the study of malignant blood disorders in Norwegian and Danish families with unrelated parents, and in the inbred ...
Names of blood container manufacturers may be found on the labels of the blood bags. The containers manufactured by Cutter Laboratories (Division of Miles), Fenwal Laboratories (Baxter Healthcare Corporation), and Terumo Corporation have been approved by CBER. Approved anticoagulants include anticoagulant...
Table 1 Abbreviations, GenBank Accession numbers, names, and chromosomal location of canine candidate reference genes evaluated. Full size table Table 2 Primer sequences, exon locations, amplicon size, and optimal melting temperature of canine candidate reference genes. Full size table Quantitative PCR...
Abbreviations CTLA-4: Cytotoxic-T-lymphocyte-associated protein 4 HD: Healthy donor ICH: Intracerebral hemorrhage NO1: Nitric oxide 1 p75 NTR: Neurotrophin receptor p75 PBMCs: Peripheral blood mononuclear cells PCA: Principal component analysis PCR: Polymerase chain reaction PI3K AKT: Phos...
Abbreviations AD: Alzheimer’s disease AUC: Area under the curve BH: Benjamini and Hochberg’s method BP: Biological process CC: Cellular component CpG: 5′—C—phosphate—G—3′ DEG: Differentially expressed gene DMG: Differentially methylated gene GEO: Gene expression omnibus GSEA:...
test results, highlighting the need for immediate, widespread standardization. A recent nationwide survey of policies and practices related to capillary blood sampling in medical laboratories in Croatia has shown that capillary sampling procedures are not standardized and that only a small proportion of ...
all NULISAseq biomarkers were represented using non-italicized upper-case gene symbols as used by the vendor. Italicized upper-case symbols were used when referring to genes. The complete list of biomarkers with their full protein names and gene symbols included in the NULISAseq panel is provided...