The U.S. Centers for Disease Control and Prevention (CDC) has reported increasing rates of alpha‐gal syndrome, an allergic response after meat ingestion (AGS). AGS has been associated with prior exposure to tick bites or other biologics characterized by a life‐threatening immunoglobulin E (IgE...
Practical and reliable enzyme test for the detection of Mucopolysaccharidosis IVA (Morquio Syndrome type A) in dried blood samples Mucopolysaccharidosis IVA (MPS IVA), or Morquio Syndrome type A, is an autosomal recessive disease caused by deficiency of the lysosomal enzyme N-acetylgal... MV...
IL32 is selectively expressed by activated cytotoxic T and natural killer (NK) cells [37], potentiates the effect of IL-2 and IL-18 and activates the innate immune system (monocytes and macrophages) to secrete chemotactic factors such as tumor necrosis factor-alpha (TNF-α), CXCL2 (11), ...
To better understand DNA methylation in Alzheimer’s disease (AD) from both mechanistic and biomarker perspectives, we performed an epigenome-wide meta-analysis of blood DNA methylation in two large independent blood-based studies in AD, the ADNI and AIB
HIF-1alpha levels were increased from 10.54±3.39 to 19.71±3.39 at the 60thsession (p=0.006) where 2 weeks post HBOT levels of 16.81±7.65 were not significantly different from baseline (p=0.16). Discussion In this study, for the first time in humans, it was found that repeated daily HB...
There is a need for a deeper understanding of antenatal depression mechanisms and the development of tools for reliable diagnosis and early identification of women at high risk. As the use of untargeted blood metabolomics in the investigation of psychiatric and neurological diseases has increased ...
(clone B4H2) was discontinued, in experiments assessing the role of CD14 in DENV-infection, anti-hCD14-IgG (clone D3B8, #mabg-hcd14) and its Human IgG1 isotype control were used (#bgal-mab1, both from InvivoGen). For viral production analysis, cells were washed after infection and ...
Further investigations of three loci have identified GALNT2 [5], TRIB1 [6], and SORT1 [7] as causative genes for blood lipid traits. However, these loci explain only a small proportion of trait variability, suggesting that many determinants remain unexplored. The pig is an important ...
E., and Lott, I. T. (2004) Down syndrome and beta-amyloid deposition. Cur Opin Neurol 17; Primavera et al., (1999) Brain Accumulation of Amyloid-beta in Non-Alzheimer Neurodegeneration. J Alzheimers Dis; Masliah et al., (2001) beta-amyloid peptides enhance alpha-synuclein accumulation...
1971). For example, a PEG adduct of adenosine deaminase was approved in the United States for use in humans for the treatment of severe combined immunodeficiency syndrome. A second advantage afforded by the conjugation of PEG is that of effectively...