With the expanding availability of clinical WGS, incorporating bioinformatic pipelines that assay the virome may be a cost-effective way to screen for these individuals. The link between endogenous viruses or viral infection and immune-related diseases is a longstanding mystery in basic and clinical ...
A RBC alloantibody responder had an antibody identified at any point during the study, and a non‐responder had a negative antibody screen at least 15 days post‐ RBC transfusion. Demographics, blood type, ICD 9/10 codes, and other potential correlates were evaluated. Of 319 177 (2·07%)...
We applied an SVD filter according to steps listed above and displayed the SVD filtered image on the screen. We used MATLAB’s ginput function to select sonication points in the brain and transformed them into FUS coordinates system using the rotation and translation matrix. We sonicated 3 foci...
et al. A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nature cell biology. 11(6), 705–16. PubMed PMID: 19465924. Pubmed Central PMCID: PMC3595613. Epub 2009/05/26. eng (2009 Jun). Article CAS PubMed...
We do not propose that this test should be used to screen the general population, but the data suggest that application of this test in conjunction with currently used structured interviews may aid in earlier and more accurate diagnosis of schizophrenia and thereby facilitate early intervention and ...
A multivariate logistic regression analysis was used to screen for independent risk factors. The odds ratio (OR) and 95% confidence intervals (CI) were also calculated, and the independent risk factor variables were used to establish a logistic regression model and calculate prediction probabilities....
elegans screen for motor dysfunctions, and controls axon guidance in all species examined25,26. Among the four vertebrate Unc5 family members, only Unc5B is expressed in ECs in mice and humans27. Unc5B binds Netrin-126,28, Robo429,30 and Flrt231,32 via its extracellular domain (ECD). ...
In order to screen interaction, binding mode, potential binding sites between in vivo components with potential targets, molecular docking between in vivo components and pathway proteins (FAK, DOCK180, Rac1, WAVE2, and Arp3) was performed. FSP, SPI, and SWE exhibited lower docking energies ...
Racial/ethnic background information was requested through a touchscreen questionnaire during the UK Biobank initial assessment center visit (UKB data-field 21000). Participants did not receive financial compensation. The analysis was restricted to homologous racial/ethnic background because of possible ...
Introduction Hypertension in childhood is a risk factor for hypertension and cardiovascular disease in adulthood.1,2,3To screen pediatric blood pressure (BP), it is necessary to clarify normal BP in childhood. Flynn et al. reported normal BP in preschool children in the United States.4On the ...