hCMEC/D3 it is a commercial cell line (Cedarlanelabs.com, CLU512, Ontario, Canada); cells are derived from human cerebral microvessel endothelial cells and are a stable, well-differentiated human BBB model (Weksler et al. 2005). Cells were cultured in EBM-2 medium (Lonza Group) supplemented...
Acknowledgements This research was funded by the Natural Sciences and Engineering Research Council of Canada (NSERC), the Canada Foundation for Innovation (CFI) and the Ontario Ministry of Economic Development and Innovation. M.C.R. is the recipient of an Early Researcher Award of the Province of...
Samuel Lunenfeld Institute for Medical Research, University of Toronto, Toronto, Ontario M5S 1A1, Canada., Lyle J. Palmer Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK., Juan P. Casas Department of Epidemiology and Public...