In the recent years, advances in biochemistry and molecular genetics have contributed to establish the structure of the genes and proteins from most of the 23 blood group systems presently known. From these findings, five functional classes of molecules can be schematically distinguished : (i) ...
Mots clés : blood group antigen ; functional diversity ; structural diversity ; structure-function relationship. Esquema Resumen Molecules with a transport or channel function The Diego antigen, Band 3, is an anion exchanger The Colton blood group antigen, AQP-1, is a water channel ...
Blood Group Systems G.Daniels, inEncyclopedia of Genetics, 2001 Structure of Blood Group Antigens Some blood groups are carbohydrate structures onglycoproteinsandglycolipids. These include the antigens of the histo-blood group systems, ABO, H, and Lewis. The genes controlling expression of thecarboh...
structure–function relationshipBiochemical and molecular genetic studies have revealed that blood group antigens are present on cell surface molecules of wide structural diversity, including carbohydrate epitopes on glycoproteins and/or glycolipids, and peptide antigens on proteins inserted within the ...
The major glycolipid based blood group A antigen of human... A blood group A glycosphingolipid with the globo-series structure has been isolated from human kidney and structurally characterized. The structure was sho... ME Breimer,Per-?ke Joval - 《Febs Letters》 被引量: 164发表: 1985...
Small amounts of more complex glycolipids with up to 10 sugar residues were identified by mass spectrometry in all cases. In addition, small amounts of lactotetraosylceramide, a blood group H-active triglycosylceramide with the structure of Fuc alpha 1-2Gal-Hex-Cer (where Fuc is fucose, ...
Genetic structure of cattle of different breeds by antigenic blood factors Aim. The study of the genetic polymorphism of erythrocyte antigens in Kalmyk, Kazakh white-headed, Hereford and Simmental cattle, to evaluate their genetic... N Chimidova,L Moiseikina,B Bolaev,... - Agrarian-And-Food ...
In blood group O individuals, the ABO locus does not encode a functional transferase enzyme. Consequently, these subjects express unmodified H antigen precursor structures. The presence of ABO(H) blood group antigens on the surface of red blood cells, and their clinical relevance in blood ...
Structure and Possible Functional Significance of Human Red Cell Blood Group Antigens (ABH, Lewis, Ii, P-related, Duffy, and Antigens on Glycophorin A). Human blood group antigens on red cells can be broadly classified into carbohydrates and proteins. The former category includes ABH, Lewis (...
Antigen structure and genetic basis of histo-blood groups A, B and O: their changes associated with human cancer1 Sen-itiroh Hakomori, in Biochimica et Biophysica Acta (BBA) - General Subjects, 1999 Blood group ABH antigens are among the first clearly-identified carbohydrates showing subtle d...