Clinical significance of the detection of Rh blood group antigens and irregular antibodies in pregnant women with a second pregnancyXiao-Ling FuXing-Dan ZhaoAi-Han WengSu-Jiao LiXue-Yu WangKai-Nian YangJournal of Hainan Medical University
Blood group antibodies play an important role in transfusion medicine, both in relation to the practice of blood transfusion and in pregnancy, but not all are clinically significant. Clinically significant antibodies are capable of causing adverse events following transfusion, ranging from mild to ...
alloantibodies; blood type; feline; Italy; neonatal isoerythrolysis; transfusion reaction1. Introduction The most clinically important and well-studied blood group system in cats is the AB system in which cats are classified as types A, B or AB based on the molecular nature of the blood group...
In subject area: Medicine and Dentistry The ABO blood group system is defined by the presence of A and B antigens on the RBC surface and anti-A and anti-B antibodies in the serum. From: Immunologic Concepts in Transfusion Medicine, 2020 ...
The frequency of irregular blood group antibodies detected for the first time in pregnant women during the period 1975-80 has been examined. Whereas Rh(D)-negative gravidae in Norway are examined immuno-hema-tologically three times during pregnancy, Rh(D)-positive women are tested once only, ...
1.2Antibodies to Blood Group Antigens Blood group antigensare useful as markers ingeneticstudies and relationship testing, and have potential associations with disease conditions, but their clinical importance lies primarily in their ability to react with antibodies that can causehemolytictransfusion reactio...
No – with each pregnancy the risk still exists of antibodies forming, should positive and negative blood become mixed. It is therefore important to make sure you continue to communicate your blood group with your future medical carers if you decide to become pregnant again. ...
, if mixing incompatible blood groups, blood clumping or agglutination will occur. That is to say, transfusion reactions or hemolytic disease of the fetus and newborn (HDFN) are usually resulted from alloantibodies produced by the exposure to a different blood group by transfusion or pregnancy....
Alloimmunization, or the formation of alloantibodies to antigens present on the red blood cell (RBC) surface, remains an important hazard of transfusion and a common adverse outcome in the setting of pregnancy. It is estimated that non-ABO blood group antibodies are detectable in up to 8% of...
ABO and H The ABO blood group system is by far the most clinically significant, because of the presence of naturally occurring IgM antibodies (and sometimes IgG). The original observation by Landsteiner that certain human erythrocyte suspensions were agglutinated by other human sera led to the ...