AS therapy is not possible for patients in whom blood donation is contraindicated. There is no consensus presently regarding a standardised AS production method, with remaining uncertainty over whether AS should be diluted before administration to reduce the concentration of tumour growth factor β,15,...
Transmission of infectious agents through blood donation [SEDA-37, 414; SEDA-38, 347; SEDA-39, 340; SEDA-40, 423] Facilities that collect and manufacture blood are under strict guidance from the Food and Drug Administration (FDA) to ensure there is uniform preparation of blood, sterility, an...
To test for a rescue effect, perfusion of kidneys deemed unsuitable for transplantation was alternated between stored and rejuvenated RBCs of the same donation. This experiment controlled oxygen-unloading, without intervening ischemia, holding all non-RBC parameters constant. Rejuvenated oxygen-unloading ...
Patients worldwide require therapeutic transfusions of packed red blood cells (pRBCs), which is applied to the high-risk patients who need periodic transfusions due to leukemia, lymphoma, myeloma and other blood diseases or disorders. Contrary to the gen
the global apheresis market was valued at $2.4 billion in 2021 and is expected to grow at a compound annual rate of 8.3% through 2031. The market’s growth is being driven by the increase in demand for blood components globally and the surge in government initiatives toward blood donation. ...
This method raises the risk of a potential infection in comparison to a singular plasma donation, as a pool can be contaminated by one single infectious donation. This justifies the intense efforts on behalf of the plasma processing industry to find methods for inactivation of at least all known...
Depending on the phenotype of an individual, different individuals' blood cells express different proteins on the surface of the red blood cells in circulation for identification by the immune system of the organism. This results in four blood types: A, O, B, and AB. Blood transfusions ...
power functionsBACKGROUND: Automated red blood cell (RBC) apheresis offers the advantage of collecting 2 units of RBCs (2RBC) from one donation, but may expose donors to procedure-related risks. This study evaluated the relative safety of 2RBC compared to whole-blood (WB) donation with a ...
A hemoglobin (Hb) wrapped covalently by human serum albumins (HSAs), a core–shell structured hemoglobin-albumin cluster designated as “HemoAct”, is an O2-carrier designed for use as a red blood cell (RBC) substitute. This report describes the blood compatibility, hemodynamic response and ph...
www.nature.com/scientificreports OPEN received: 01 June 2016 accepted: 05 January 2017 Published: 07 February 2017 SpotLight Proteomics: uncovering the hidden blood proteome improves diagnostic power of proteomics Susanna L. Lundström1, Bo Zhang1, Dorothea Rutishauser1, Dag Aarsland2,...