Pre-eclampsia is associated with asymptomatic global left ventricular dysfunction and abnormal geometry during the acute phase of the disorder. One year postpartum, asymptomatic left ventricular moderate-severe dysfunction and hypertrophy were significantly higher in preterm eclampsia (56%) compared to term...
et al. improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate. plos genet. 2013;9:e1003455. liu jz, hov jr, folseraas t, ellinghaus e, rushbrook sm, doncheva nt, et al. dense genotyping of immune-relat...
The purpose of the present study was to construct a preliminary diagnostic model to distinguish major depressive disorder (MDD) and bipolar disorder (BD) using potential commonly tested blood biomarkers.#Information of 721 inpatients with an ICD-10 diagnosis of MDD or BD were collected from the ...
myelofibrosis (MF), polycythemia vera (PV), and essential thrombocytosis (ET)10,11,12,13,14,15,16,17. There are silent bystanders within this polygenic model of susceptibility (persons having congenic susceptibility without developing the pathognomonic mutation), and there is a range of aggressive...
(ICD)-9/10 chapters, that might share causes and similar associations with blood group, i.e., circulatory, endocrine, respiratory, neoplasms, digestive, neurological, musculoskeletal, gynecologic and obstetric, hematopoietic, dermatologic, genitourinary, mental health, infectious diseases, sense organs, ...
Atherosclerosis and endometriosis: the role of Diet and oxidative stress in a gender-specific disorder. Biomedicines. 2023;11:450. Article CAS PubMed PubMed Central Google Scholar Crook D, Howell R, Sidhu M, Edmonds DK, Stevenson JC. Elevated serum lipoprotein(a) levels in young women with ...
Niemann-Pick type C (NPC) disease is one kind of sphingolopodosis due to a neurodegenerative lysosomal storage disorder. High-resolution 1H-NMR spectroscopy metabolomic profiling coupled with advanced multivariate analysis methods revealed significant difference in the plasma of Niemann-Pick C1 (NPC1)...
Mitral valve prolapse (MVP) is a common heart disorder characterized by an excessive production of proteoglycans and extracellular matrix in mitral valve leaflets. Large-scale genome-wide association study (GWAS) underlined that MVP is heritable. The molecular underpinnings of the disease remain largely...
Channelopathies are usually caused by a disorder in which there is a mutation in one of the genes that determine the make up of heart cell channels. However, some people develop a channelopathy as a complication of certain autoimmune or inflammatory disorders, such as systemic lupus erythema...
The disorder is prevalent in all major ethnic groups, although Blacks are disproportionately affected [1]. As elevated BP is a strong and independent risk factor for car- diovascular and renal disease morbidity and mortality [2], identifying preventive measures is an importa...