The blood-brain barrier (BBB) serves as a highly intricate and dynamic interface connecting the brain and the bloodstream, playing a vital role in maintaining brain homeostasis. BBB dysfunction has been associated with multiple neurodegenerative diseases
Poly(ethylene glycol) conjugated polyamidoamine dendrimers have also been used as vehicles for the delivery of drugs and reducing blood clotting for ischemic stroke therapy [54]. The delivery of drugs across the blood-brain barrier to treat hypothermic circulatory arrest was achieved by using ...