CD45RA+ CD4 cells and CD45RA+/CD45RO+ double-positive cells were less affected by CdA. Activated T cells, ie, HLA-DR+ cells, rarely decreased below the normal range and often recovered with an overshoot. CD10+ cells increased in the bone marrow posttreatment as an indication of normal...
Flow cytometry of blood and bone marrow cells from patients with hairy cell leukemia: phenotype of hairy cells and lymphocytes subsets after treatment with 2-CdA. Blood 1994: 83: 3679-3681.Juliusson G, Lenkei R, Liliemark J. Flow cytometry of blood and bone marrow cells from patients with ...
the early marrow normoblasts might behave like its counterpart in the fetal bone marrow in producing i substance (210). The normoblasts duringthe course of their maturation either utilize i for conversion to I or else shift from i to I through a “switch” mechanism analogous to the change...
Functional characterization of CD4+CD25+ regulatory T cells differentiated in vitro from bone marrow-derived haematopoietic cells of psoriasis patients wit... SummaryBackground In psoriasis CD4+CD25+ regulatory T cells are functionally deficient. The imbalance between regulatory and effector T-cell fu...
Your baby's cord blood will be kept exclusively for your family and will be available for use whenever the cord blood is needed. Fully payable with CDA If you're a Singapore citizen, you can use your Baby Bonus or Child Development Account to pay for our cord blood banking packages, elim...
第八節輸血及骨髓移植Blood Transfusion and Bone Marrow Transplantation 通則: 一、輸血以大手術及外傷等嚴重之組織損傷或失血過多及嚴重特殊疾病,危及生命,其他藥物不能救急時為之。 二、保險對象在同一特約醫療院所門診或住院第一次輸血時,得申報血型測定(ABO typing)及Rh血型檢查(Rh type)各一次。如有必要得申...
IL-6 is a pleiotropic cytokine involved in not only immu- nity and inflammation but also bone metabolism and neural development (6). IL-6 also stimulates the proliferation of cul- tured vascular smooth muscle cells (7), indicating that this cytokine may play an important role in the ...
We have shown t h a t fibrin-monomer- f i b r i n o g e n complexes induce a marked r i s e i n RBC aggregation i n b o t h neonatal and a d u l t blood. Since the complexes are formed as a r e s u l t o f endotoxinaemia, they might caenia c.oTnhtersi be...
另一种酶,胞苷脱氨酶(CDA),通过其不可逆的脱氨到非活性代谢物,阿拉伯尿苷,抑制阿糖胞苷。CDA过表达被认为是AML患者阿糖胞苷耐药的可能机制,即CDA低表达与较长缓解时间相关【3】。上述机制——hENT1功能缺失突变、DCK表达减少和CDA过表达——已被证...
infusion, 2 hours after 2-CdA infusion, days 1-7 and 2-CdA 5 mg/m2, 2-hours i.v. infusion, days 1-5). Bone marrow (BM) aspiration to assess the treatment response was performed on days from 28 to 42 following the induction cycle. After achieving a CR, the patients of both ...