protein-coding gene 同源简称(alias symbol) BS|RECQL3|RECQ2 基因家族代码(gene_family_id) [HGNC][GenScript] omim代码 604610 entrez码 641[Vega] ensembl基因码 ENSG00000197299[Ensembl] 基因家族(gene family) refseq数据库代号 NM_000057 更多... ...
In order to investigate the differential expression of BLM protein in hematopoietic tumor cell strains and study the effects of BLM gene on ultraviolet (UV)-or hydroxyurea (HU)-induced apoptosis, Western blot was used to detect the expression of BLM protein in normal human bone marrow mononuclear...
bloom综合征基因产物与含有dna解旋酶的desh盒recq亚群有关,具有dna刺激的atp酶和atp依赖的dna解旋酶活性。引起布鲁姆综合征的突变会删除或改变螺旋酶基序,并可能使3'-5'螺旋酶活性丧失。正常蛋白可能起到抑制不适当重组的作用。[由RefSeq提供,2008年7月]The Bloom syndrome gene product is related to the RecQ sub...
Gene SummaryThe Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity...
提供的BLM人源重组蛋白(Q01)产品为带有GST标签的人源BLM部分序列重组蛋白,其对应的GeneID号为641。 产品描述 与其它公司提供的重组蛋白不同,该BLM人源重组蛋白(Q01)产品为采用CFS的无细胞麦胚蛋白合成系统表达出来的重组蛋白,可表达出对细胞有毒性、易被蛋白酶降解的蛋白;并获得具有良好的可溶性,并有翻译后修饰、...
注:该品系与LGB-cre工具鼠交配才可能获得预期表型 参考文献 Chester N, Babbe H, Pinkas J, Manning C, Leder P, Mutation of the murine Bloom's syndrome gene produces global genome destabilization. Mol Cell Biol. 2006 Sep;26(17):6713-26 查看更多 你也可能感兴趣...
However, the post-transcriptional control regulation of BLM gene expression is not fully understood and limits the application of drugs targeting BLM for carcinoma therapy in the future. MicroRNAs (miRNAs) inhibit gene expression through interaction with the 3 ' untranslated region (3 '-UTR) of ...
Bloom syndrome (BS) is caused by homozygous or compound heterozygous mutations in the RecQ DNA helicase gene BLM . Since the molecular isolation of BLM , characterization of BS-causing mutations has been carried out systematically using samples stored in the Bloom's Syndrome Registry. In a survey...
(BSISTER) transcript factors, a member of the MADS-BOX gene family, regulate the biosynthesis of stilbenes in grapevine. Comprehensive transcriptome and phenolic metabolome analysis were conducted on wild-type grapevine callus, as well as on transgenic callus overexpressing 35S::VviBS1-GFP and 35S:...
Past Television (3 titles) Episodes Wenn Essen auf die Gene schlägt (2009) (TV Movie) - Production company Hitec - Gefährliche Mahlzeiten (2009) (TV Movie) - Production company Von Göttern und Designern (2006) (TV Movie) - Production company COMPANY...