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AEs associated with garetosmab included epistaxis, madarosis and a composite of skin and soft-tissue infections. Investigation of coagulation function and BMP9 levels did not provide definitive insights into the potential mechanisms of epistaxis. These AEs had not been observed in two previous early-...
Discrepancy Between Subjective and Objective Sleep Disturbances in Early- and Moderate-Stage Alzheimer Disease. Am J Geriatr Psychiatry. 2012;20:460–7. Article PubMed Google Scholar Bliwise DL, Hughes M, Mcmahon PM, Kutner N. Observed Sleep/Wakefulness and Severity of Dem...
One or more interim analyses were planned for the purpose of evaluating potential early stopping for an efficacy conclusion after a minimum of 166 subjects had completed the double-blind period and primary endpoint data were available for approximately 145 subjects. A conservative alpha spending functio...
Wiley Subscription Services, Inc., A Wiley CompanyPediatric PulmonologyBallard HO, Shook LA, Bernard P, Anstead MI, Kuhn R, Whitehead V, et al. Use of azithromycin for the preven- tion of bronchopulmonary dysplasia in preterm infants: a randomized, double-blind, placebo controlled trial. ...
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In October, Stacy and I founded Blind Early Services TN, also known as BEST, a nonprofit organization supporting families of children, ages 0-5, who are blind or visually impaired. And as you can probably guess, we are modeling ourselves after VIPs and other agencies in other states who ha...
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The early insulin secretion index (∆PI30-0/∆PG30-0) was calculated as the change in PI from 0-min to 30-min divided by the change in PG over the same period [34]. The ISSI-2 is an OGTT-derived measure of β-cell function, calculated by the product of the ratio: total ...
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