Entrez-Gene Id: 639 View in PhosphoSitePlus®限制使用 除非CST 的合法授书代表以书面形式书行明确同意,否书以下条款适用于 CST、其关书方或分书商提供的书品。 任何书充本条款或与本条款不同的客书条款和条件,除非书 CST 的合法授书代表以书面形式书独接受, 否书均被拒书,并且无效。 专品...
Gene Name: PRDM1 Protein Name: PR domain zinc finger protein 1 Human Gene Id: 639 Swiss-Prot: O75626 Formulation: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol. Source: Monoclonal, Mouse Dilution: WB: 1:500-1:2000 ELISA: 1:10000 PurIF:ication: Affinity purIF:icati...
The researchers further traced this observation to a gene called Prdm1 encoding the proteinBLIMP-1, increased expression of which leads to differentiation and proliferation of plasma cells in B cell immune response (Figure 2). Kurosaki, ERKs induce expression of the transcriptional repressorBlimp-1and...
446 The PRDM1/ BLIMP1 gene encodes a zinc finger transcriptional repressor that is expressed in a subset of germinal center (GC) B cells and in all plasma cells, and is required for terminal B cell differentiation. The BLIMP1 locus is biallelically inactivated by structural alterations in ...
et al. Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity 17, 51–62 (2002). Article CAS Google Scholar Sciammas, R. & Davis, M.M. Modular nature of Blimp-1 in the regulation of gene expression during B cell maturation. ...
6. Chihara, N., Madi, A., Kondo, T., Zhang, H., Acharya, N., Singer, M., et al. (2018). Induction and transcriptional regulation of the co-inhibitory gene module in T cells. Nature 558 (7710), 454–459.
说明书 实验方案 技术支持 货号14-5963-80 View price in cart 25 µg100 µg 下单后预计有货时间 21-Mar-2025 查看价格 批量或定制请求 抗体检测数据 (3) 已发表图片 (28) 高级验证 (1) Application Created with Sketch. 图:1/32 Blimp-1 Antibody (14-5963-80) in IHC (P) ...
这个基因编码一种蛋白质,作为β-干扰素基因表达的抑制剂。该蛋白与β-干扰素基因启动子的prdi(阳性调节域i元件)特异性结合。这种基因的转录随着病毒的诱导而增加。已经报道了两种编码不同亚型的选择性剪接转录变体。This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The pr...
terminal differentiation of B lymphocytes and monocyte/macrophages. Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells. It has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene ...
It has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression. 显示更多 + 研究领域 心血管 心血管 血管学 心血管 心血管发育 免疫学 免疫学 先天免疫学 免疫学 适应性免疫学 產品图片 GTX30605 IHC-P Image IHC-P analysis of human tonsil...