A. White. 1990. Bleomycin-induced pulmonary toxicity. Clin. Chest Med. 11: 1-20.Jules-Elysee K, White DA (1990) Bleomycin-induced pulmonary toxicity. Clin Chest Med 11: 1-20.Jules-Elysee, K., White, D.A., 1990.
Poster: HL-172 FDG-PET/CT as a Tool for Early Detection of Bleomycin-Induced Pulmonary Toxicity Clinical Lymphoma Myeloma and Leukemia Volume 22, Supplement 2, October 2022, Page S162 Purchase options CorporateFor R&D professionals working in corporate organizations. Academic and personalFor academic...
The major limitation of bleomycin therapy is pulmonary toxicity and may be life threatening in about 10% of cases. This article reports a case of an ovarian mixed germ cell tumour, which presented with bleomycin-associated pulmonary toxicity....
Soluble epoxide hydrolase inhibitor AUDA decreases bleomycin-induced pulmonary toxicity in mice by inhibiting the p38/Smad3 pathways. Toxicology. 2017;389:31–41. https://doi.org/10. 1016/j.tox.2017.07.002. 5. Cui K, Kou JQ, Gu JH, et al. Naja naja ...
Bleomycin is a chemotherapeutic agent commonly used to treat curable diseases such as germinative tumors and Hodgkin???s lymphoma. The major limitation of bleomycin therapy is pulmonary toxicity, which can be life threatening in up to 10% of patients receiving the drug. The mechanism of bleomycin...
Recently, (5R)-5-hydroxytriptolide (LLDT-8), a new compound derived from triptolide, was syn- thesized and showed similar immunosuppressive activity to that of triptolide, but its toxicity was greatly reduced in vitro and in vivo. In vitro, LLDT-8 significantly inhibited 518 ©2007 CPS and...
bone tumor, digestive tract tumor, blood system tumor and other cancers in order to reduce the toxicity of chemotherapy drugs, and recent studies have reported that the drug can also reduce lung tissue damage in patients with pulmonary fibrosis, but its mechanism of action is not yet fully unde...
Bleomycin-induced pulmonary fibrosis in the rat: inhibition by indomethacin. Am J Pathol. 1979;95(1):117–30. CAS PubMed PubMed Central Google Scholar Muggia FM, Louie AC, Sikic BI. Pulmonary toxicity of antitumor agents. Cancer Treat Rev. 1983;10(4):221–43. https://doi.org/...
We previously reported that spermidine levels were significantly reduced in idiopathic pulmonary fibrosis (IPF) of the lung. The present study assessed the potential beneficial effects of spermidine on lung fibrosis and investigated the possible mechanism. Lung fibrosis was established in mice using ...
While the acute inflammatory phase of bleomycin-induced pulmonary toxicity is dominated by neutrophil activity, the later phases of injury progression, resolution and fibrogenesis are regulated by macrophages (Misharin et al., 2017). These cells include tissue resident macrophages, which are pivotal in...