由于BLA和ACC都参与了MK-801诱导的精神分裂症样行为,课题组由此探究了BLA-ACC环路对小鼠行为表型的调控作用。原位杂交结果表明,BLA向ACC发送投射的神经元是谷氨酸能神经元。 行为学结果显示;化学遗传或光遗传激活BLA-ACC投射缓解了MK-801小鼠的社交缺陷,并增强了其在新物体识别测试中的认知能力,而化学遗传或光遗传抑...
在恐惧调节方面，BLA-ACC环路被认为能够通过调节杏仁核和前扣带回皮层之间的相互作用来抑制恐惧反应。具体...
结果显示:抑制BLA-ACC环路,可以翻转慢性疼痛小鼠本来的放弃奖赏避开厌恶型的冷环境;兴奋BLA-ACC环路,可以模拟慢性疼痛小鼠的放弃奖赏避开厌恶性的冷环境的趋避行为。这表明BLA-ACC环路是影响小鼠冲突抉择的趋避行为的充要条件。 图4.LFS离体光兴奋BLA-ACC环路传递受限,减少SNI小鼠在冲突任务中回避行为 最后,光遗传学兴...
ACC到BLA的直接神经投射也参与了恐惧学习等情感功能。rACC与杏仁核之间的关联在多种神经和精神障碍(包括神经病理性疼痛)中增加,而ACC-BLA通路中同步化θ波振荡的破坏被认为会导致大鼠的情感和认知缺陷。此外,跨频率相干性在信息处理和检测场电位振荡的广泛相关性以及不同脑区之间的同步化方面具有功能意义,可能反映这些...
Allergic inflammation also enhanced neuronal activities and functional connectivity of the ACC-BLA circuit which were correlated with the level of anxiety. Together, we suggest that disruption in the dynamic oscillatory activities of the ACC-BLA circuit, maybe due to regional inflammation, is an ...
1.3 FILLING THE BLA NKS access;edge;scenery;border,aa a2fasten;stream;rocky,steep.a∈ot_1-3t-2;teenagers;handkerchief;ach eved accoae① The system was designed to give the user quick and easy2 The books are by four CDs.3 She finally her ambition to visit South America.4 She her belt...
综上所述,ACC-vmPFC和BLA-vmPFC回路在连接其他休克和自我僵直的神经表征中都发挥了重要作用。ACC-vmPFC和BLA-vmPFC具有相反的功能;前者参与了僵直负/休克激活神经元的活动,后者参与了僵直正/休克抑制神经元,表明两种不同的通路协同处理基于其他状态的神经表征自我状态。
具体方法如下:以地衣芽孢杆菌基因组为模板,通过引物对(bla-f1:cgggatccgagacgatgaaacaacaaaaacggctttacg和bla-r1:cccaagcttctatctttgaacataaattgaaaccgacc)扩增,pcr反应体系:10×pfubuffer,5μl;dntp(2.5mm),2μl;正向引物(10μm),2μl;反向引物(10μm),2μl;pfu聚合酶,2μl;模板,1μl;加ddh2o至...
Overview of the High Efficiency Video Coding(HEVC) Standard G. 帧内预测 Intrapicture Prediction Fig. 6. Modes and directional orientations for intrapicture prediction. Intrapicture prediction operates acc... HEVC块划分 块划分 每帧图像被划分成固定尺寸的 CTU (Coding Tree Unit),每个 CTU 包含 1 个...
1) component glow wire resistant (GWT 750 °C), testing acc. to IEC 60695-2-11, assessment acc. to IEC 60335-1 (flame < 2 s) 机械数据 Mating with:tab contact 6.3 mm x 0.8 mm according to DIN 46244 Insertion force:≤ 95 N *1 Withdrawal force:≥ 45 N *2 1) measured at a ma...