Using another cohort of hCTLA-4 mice inoculated with MC38 cells, we treated animals (n = 5 per group) with ipilimumab, anti-PD-1, anti-PD-1 plus D11, D11 alone, or vehicle in the same dosages as used previously. Some animals’ tumors were collected approximately 10 days after ...
2Intercenter Cancer Research Group, Florida, 3Pacific Shores Medical Group, California. 4Medarex, Inc., New Jersey, USA. Aim: To evaluate the bispecific antibody MDX-H210 (which combines a recognition site for HER-2/neu with a triggering sequence for the high affinity IgG Fc receptor CD64)...