Chronic hepatitis B: A wave of new therapies on the horizon Timothy M. Block, ... Carol L. Brosgart, in Antiviral Research, 2015 4.1.4 Birinapant Birinapant from Tetralogic Corp, is a small molecule that is believed to mimic second mitochondrial activator of caspases (SMAC) (Seigal et al...
Birinapant/TL32711 ( 1 ) is a novel bivalent antagonist of the inhibitor of apoptosis (IAP) family of proteins which is currently in clinical development for the treatment of cancer and hepatitis B virus (HBV) infection. In this report, we present a detailed description of the 1 drug ...
Phase I/II Acute myeloid leukaemia; Hepatitis B; Precursor cell lymphoblastic leukaemia-lymphoma Phase I Non-Hodgkin's lymphoma No development reported Head and neck cancer; HIV infections; Legionella infections; Lymphoma; Pancreatic cancer; Tuberculosis Most Recent Events 28 Feb 2023 No recent ...