Only 20% of the veterans who reported SB had a corroborating ICD-9/10 EHR code. Among those without prior SB, more than 20% reported new-onset SB at follow-up. SB were associated with a range of additional clinical diagnoses, and with treatment with specific classes of psychotropic ...
The lifetime prevalence (LTP) of both schizophrenia and bipolar I (BPI) disorder is often assumed to be about 1%. However, in a recent systematic review, the median LTP of schizophrenia was only 0.4%.1 Recent population-based surveys in particular have found considerably lower LTPs of schizoph...
Both subtypes impact daily functioning, with the severity of manic episodes distinguishing the two [1]. The average age of onset for bipolar I disorder is 18 years, while for bipolar II disorder, it is 20 years [2]. The prevalence of bipolar disorder is similar for both males and females...
The primary predictor was bipolar disorder (code F31 in the International Statistical Classification of Diseases, 10th Revision [ICD-10]), which was identified by any outpatient or inpatient diagnosis during the preceding 2 years (January 1, 2001, through December 31, 2002) using the Swedish ...
The ability to classify patients with bipolar disorder (BD) is restricted by their heterogeneity, which limits the understanding of their neuropathology. Therefore, we aimed to investigate clinically discernible and neurobiologically distinguishable BD subtypes. T1-weighted and resting-state functional magnet...
Bipolar disorder is a severe mental illness characterized by recurrent manic and depressive episodes. To better understand its genetic architecture, we analyze ultra-rare de novo mutations in 354 trios with bipolar disorder. For germline de novo mutation
(1) All participants were required to meet the diagnostic criteria for bipolar disorder (F31) in the International Statistical Classification of Diseases and Related Health Problems, 10th edition (ICD-10). F31 bipolar affective disorder is characterised by two or more episodes in which the patient...
Statistical Manual of Mental Disorders (DSM)-5 and the upcoming International Classification of Diseases (ICD)-11 classification systems on the prevalence of bipolar disorder and on the validity of the DSM-5 diagnosis of bipolar disorder according to the Robin and Guze criteria of diagnostic ...
ContextSeveral studies have suggested that lithium treatment reduces risk of suicide in bipolar disorder, but no research has examined suicide risk
This study investigates the cellular origin and tissue heterogeneity in bipolar disorder (BD) by integrating multiomics data. Four distinct datasets were employed, including single-cell RNA sequencing (scRNA-seq) data (embryonic and fetal brain, n =