This method was applicable to a large-scale synthesis, and optimized reaction conditions have been investigated.Bret E. HuffChemical Process Research and Development, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, INThomas M. Koenig...
3-Fluoro-3'-(2-methylpropyl)[1,1'-biphenyl]-4-carboxaldehyde Usage And Synthesis 3-Fluoro-3'-(2-methylpropyl)[1,1'-biphenyl]-4-carboxaldehyde Preparation Products And Raw materials Tag:3-Fluoro-3'-(2-methylpropyl)[1,1'-biphenyl]-4-carboxaldehyde(1715703-25-5) Related Product Information ...
The invention relates to a method or process for the manufacture of blood pressure lowering agents, such as valsartan, novel intermediates as well as process steps in said synthesis. The method or process leads via the novel intermediate salts of the formula IAGottfried Sedelmeier...
Huff B E,Thomas M K,David M,Michael A S.Synthesis of unsymmetrical biaryls using a modified suzuki cross-coupling: 4-biphenylarboxyaldehyde. Organic Synthesis . 2004Huff, et al., " Synthesis of Unsymmetrical Biaryls Using a Modified Suzuki Cross-Coupling: 4-Biphenylcarboxaldehyde ". In Organic...
The invention relates to a method or process for the manufacture of blood pressure lowering agents, such as valsartan, novel intermediates as well as process steps in said synthesis. The method or process leads via the novel intermediate salts of the formula IA, or a tautomer thereof, wherein...
Valsartan, new compounds and intermediates as well as steps to the synthesis Almdhk The ORP.Lead the way and process to new salts of intermediate language IA or similar vehicles, which is n] + [Kat positive ion and N accounted for 1,2,3,4. The, 5 or 6.JRIMLR, DOMINIQUE...
The invention relates to a method or process for the manufacture of blood pressure lowering agents, such as valsartan, novel intermediates as well as process steps in said synthesis. The method or process leads via the novel intermediate salts of the formula IA,;\n\n\nor a tautomer thereof,...
FIELD: chemistry.;SUBSTANCE: described is a method of producing novel intermediate compounds - salts of formula or tautomers thereof, where [Kat]n+ denotes an alkali metal cation and n equals 1, compounds themselves and use thereof in valsartan synthesis.;EFFECT: obtaining novel intermediate ...
A preparation method of 2-butyl-4-chloro-1-[[2-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]imidazole-5-carboxaldehyde is provided to improve preparation yield and economic efficiency of the compound via synthesis of a novel intermediate represented by the formula(8), and apply the method to the...