If the results of the immunology assays performed on Cobas e602 may be affected when patient is treated with biotin with doses equal or greater than 5 mg, 3 times a day, this effect will be noticeable only for certain parameters like TSH, FT4, FT3, TnThs and PCT....
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The rate of hydrolysis is significantly increased by metallic cation (Mg ++), a specific effect which allows to consider characterization of selectivity of bond breaking between nitrogen and carboxylate group with other nucleophiles.doi:10.1016/S0040-4020(01)96678-5Par E. Monnier...